Development of a Plasma-Based Assay to Measure the Susceptibility of Factor V to Inhibition by the C-Terminus of TFPI α.

CONCLUSION: We have developed and validated an assay that measures the susceptibility of plasma FV to the TFPIα C-terminus. Once automated, this assay may be used to test whether the TFPIr correlates with thrombosis or bleeding risk in population studies. PMID: 31705518 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31705518?dopt=Abstract

Source: Thrombosis and Haemostasis - November 7, 2019 Category: Hematology Authors: van Doorn P, Rosing J, Campello E, Middeldorp S, Simioni P, Meijers JCM, Hackeng TM, Castoldi E Tags: Thromb Haemost Source Type: research

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