Risk of Type 1 Diabetes in the Offspring Born through Elective or Non-elective Caesarean Section in Comparison to Vaginal Delivery: a Meta-Analysis of Observational Studies

ConclusionSummarized crude risk estimates showed a small increased T1D risk in children and young adults born through elective CS compared to vaginal delivery, but with significant heterogeneity. Adjusted risk estimates by study design indicated a slightly increased T1D risks associated with elective or non-elective CS.
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research

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Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Although most patients with type 1 diabetes (T1D) retain some functional insulin-producing islet β cells at the time of diagnosis, the rate of further β cell loss varies across individuals. It is not clear what drives this differential progression rate. CD8+ T cells have been implicated in the autoimmune destruction of β cells. Here, we addressed whether the phenotype and function of autoreactive CD8+ T cells influence disease progression. We identified islet-specific CD8+ T cells using high-content, single-cell mass cytometry in combination with peptide-loaded MHC tetramer staining. We applied a new analyti...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Diabetes Dad Brendan McEachern in Cincinnati has written a book from the perspective of an 11-year-old with type 1 diabetes.
Source: Diabetes Mine - Category: Endocrinology Authors: Source Type: blogs
Condition:   Type1 Diabetes Intervention:   Other: Team Clinic Sponsors:   Children's Hospital Los Angeles;   University of Colorado Denver School of Medicine Barbara Davis Center;   Cedars-Sinai Medical Center Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Diabetes Mellitus, Type 1;   Closed-Loop Interventions:   Device: Open-loop condition;   Device: Closed-loop condition Sponsor:   Centre d’Etudes et de Recherche pour l’Intensification du Traitement du Diabète Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
MONDAY, Dec. 9, 2019 -- Skyrocketing prices and insurance limits are driving many people with diabetes to seek medications and supplies from an underground supply chain, a new study found. " The cost of insulin, which is required in type 1 diabetes...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
According to a study published inDiabetologia, preterm birth may increase risk of developing type 1 and type 2 diabetes in adulthood.Med Page Today
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Funding Opportunity RFA-DK-19-022 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits U01 applications for the establishment of a clinical consortium, composed of one Data Coordinating Center (DCC) and up to 10 Clinical Centers (CC), to conduct studies on diabetes mellitus, with an emphasis on Type 1 diabetes (T1D), that occurs after or as a consequence of one or more episodes of acute pancreatitis. The Consortium will form multi-disciplinary teams composed of members from the CCs and DCC to undertake a prospective longitudinal observational study of the occurrence of diabetes...
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
Funding Opportunity RFA-DK-19-023 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits U01 applications for the establishment of a clinical consortium, the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC), composed of one Data Coordinating Center (DCC) and up to 10 Clinical Centers (CC), to conduct studies on Type 1 diabetes mellitus (T1D) that occurs after or as a consequence of one or more episodes of acute pancreatitis. Applications for the Clinical Centers (CC) are submitted in response to a separate FOA: RFA-DK-19-022: Type 1 Diabetes in Acute Pancreatitis Consort...
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
Source: Journal of Pediatric Endocrinology and Metabolism - Category: Endocrinology Source Type: research
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