Testosterone Restoration by Enclomiphene Citrate in Men with Secondary Hypogonadism: Pharmacodynamics and Pharmacokinetics

ConclusionsEnclomiphene citrate increased serum LH and TT; however, there was not a temporal association between the peak drug levels and the Cmax levels LH or TT. Enclomiphene citrate consistently increased serum TT into the normal range and increased LH and FSH above the normal range. The effects on LH and TT persisted for at least one week after stopping treatment.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fbju.12363

Source: BJU International - July 12, 2013 Category: Urology & Nephrology Authors: Ronald Wiehle, Glenn R. Cunningham, Nelly Pitteloud, Jenny Wike, Kuang Hsu, Gregory K. Fontenot, Michele Rosner, Andrew Dwyer, Joseph Podolski Tags: Sexual Medicine Source Type: research