New potential modulators of CYP4F2 enzyme activity in angina pectoris: hsa-miR-24-3p and hsa-miR-34a-5p.

Conclusions. Our data suggests that hsa-miR-24-3p might have an effect on CYP4F2 activity during atherosclerosis. PMID: 31694408 [PubMed - as supplied by publisher]
Source: Biomarkers - Category: Research Tags: Biomarkers Source Type: research

Related Links:

Publication date: Available online 7 December 2019Source: Revista Española de Cardiología (English Edition)Author(s): Carlos Escobar, Manuel Anguita, Vicente Arrarte, Vivencio Barrios, Ángel Cequier, Juan Cosín-Sales, Isabel Egocheaga, Esteban López de Sa, Luis Masana, Vicente Pallarés, Leopoldo Pérez de Isla, Xavier Pintó, José Ramón González Juanatey, José Luis ZamoranoAbstractThe current control of low-density lipoprotein cholesterol among patients with atherosclerotic cardiovascular disease is very low and this is associated with an inc...
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
Publication date: Available online 7 December 2019Source: American Heart JournalAuthor(s): Sarah T. Ahmed, Dhruv Mahtta, Hasan Rehman, Julia Akeroyd, Mahmoud Al Rifai, Fatima Rodriguez, Hani Jneid, Khurram Nasir, Zainab Samad, Mahboob Alam, Laura A. Petersen, Salim S. ViraniBackgroundStatin use remains suboptimal in patients with atherosclerotic cardiovascular disease (ASCVD). We assessed if the frequency of visits with primary care providers (PCPs) is associated with higher use of evidence-based statin prescriptions and adherence among patients with ASCVD.MethodsWe identified patients with ASCVD aged ≥18 years rec...
Source: American Heart Journal - Category: Cardiology Source Type: research
CONCLUSIONS: This study did not support an association between statin use and diagnostic conversion but suggested a possible association between statin use and cognitive change in EMCI. Additional randomized clinical trials of statins may be warranted in the prodromal EMCI stage of AD. PMID: 31806426 [PubMed - as supplied by publisher]
Source: The American Journal of Geriatric Psychiatry - Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research
ConclusionSignificant moderate association between CRP and several blood tests was evaluated in apparently healthy population. This information should be used for further studies of the relationship between inflammation and biological processes.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Authors: Sevim E, Willis R, Erkan D Abstract Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by thrombosis, pregnancy morbidity, or nonthrombotic manifestations in patients with persistently positive antiphospholipid antibodies (aPL). Conventional APS treatment focuses on antithrombotic strategies, which are usually ineffective for the microvascular and nonthrombotic manifestations of aPL. Using a case-based presentation, this review focuses on the role of immunosuppression in nonobstetric APS, including B-cell inhibition (rituximab, belimumab, and bortezomib), complement inhibition ...
Source: Hematology ASH Education Program - Category: Hematology Tags: Hematology Am Soc Hematol Educ Program Source Type: research
Discussion–conclusionThe findings of this study suggest that caution should be taken when prescribing Statins in older adults, as this could decrease ML stability and ultimately increase fall risk.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
We present normally distributed variables using means and standard deviations and non-normally distributed variables using medians along with their ranges. Spearman's correlation coefficients were used to analyse correlations between the CSF's biomarker concentrations, and both unadjusted and Bonferroni adjusted p-values are reported. Orthogonal projection to latent structure discriminant analysis (OPLS-DA) was also used to find differences in terms of CSF metabolites between the relapsing and remitting patients [CIS, RR, PR versus PP, SP patients]. The OPLS-DA algorithm finds the projection direction, score vector, that g...
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
The Pharmacogenomics Journal, Published online: 06 December 2019; doi:10.1038/s41397-019-0136-7Genetic contribution to lipid target achievement with statin therapy: a prospective study
Source: The Pharmacogenomics Journal - Category: Drugs & Pharmacology Authors: Source Type: research
ConclusionsThere was a significant association between statin use and TUG inability in older Chinese inpatients with diabetes.
Source: The Journal of Nutrition, Health and Aging - Category: Nutrition Source Type: research
To prevent heart problems later in life, people 45 and younger with higher levels of bad cholesterol might want to change their eating and exercise habits, or even talk to their doctor about medications such as statins, a new study says.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
More News: Atorvastatin Calcium | Genetics | Lipitor | Research | Statin Therapy | Zivast