The influence of morphological distribution of melanin on parameter selection in laser thermotherapy for vascular skin diseases

In this study, 10 different morphological distributions of melanin were proposed according to the formation and migration characteristics of melanin, and the two-scale heat transfer model was employed to investigate the influence of melanin distribution on the threshold radiant exposure of epidermis and blood vessels. The results show that melanin distributions do have a strong effect on laser parameter selection. When uniform melanin distribution is assumed, the threshold radiant exposure to damage a typical PWS blood vessel (50  μm diameter) is 8.62 J/cm2 lower than that to injure epidermis. The optimal pulse duration is 1 –5 ms for a typical PWS blood vessel of 50 μm when melanin distribution is taken into consideration. PWS blood vessels covered by non-uniformly distributed melanin are more likely to have poor response to laser treatment.
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research

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Source: Journal of Cosmetic and Laser Therapy - Category: Laser Surgery Authors: Source Type: research
Source: Journal of Cosmetic and Laser Therapy - Category: Laser Surgery Authors: Source Type: research
ConclusionsIntravaginal laser therapy led to cure/improvement for SUI I and SUI II, but not for severe SUI III. Outcome was better after four to five laser sessions than after two laser sessions. Follow-up data  6 months and 2 years after laser intervention showed sustainability of the treatment.
Source: International Urogynecology Journal - Category: OBGYN Source Type: research
ConclusionsThe aim of this case report is to describe our surgical strategy to manage a giant vascular malformation of the tongue and improve quality of life through a median glossectomy with trapezoidal wedge resection of the tongue, as previously described for surgical management of macroglossia.
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - Category: ENT & OMF Source Type: research
Conclusion: LLLT+PN alleviated DH at all time intervals, with a greater effect in the fluorotic group. However, LLLT+PN was more efficacious in reducing DH at 12 weeks post treatment in the fluorotic group.
Source: Oral health and Preventive dentistry - Category: Dentistry Source Type: research
AbstractStroke results in impairment of basic motor functions, such as muscle weakness in limbs affected by spasticity, leading to peripheral fatigue and impaired functionality. The clinical use of photobiomodulation therapy (PBMT) has provided major advances in the treatment of muscular disorders and prevention of muscle fatigue. The aim of this study was to analyze the effects of two distinct therapies in biceps spasticity of chronic hemiparetic patients. We analyzed range of elbow motion, torque, electromyography, and mean spectral frequency after 10 sessions of PBMT (Laser 100 mW, 808 nm, 159.24 J/cm2/point, 5 J/point)...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
Publication date: Available online 4 December 2019Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Auriléia Aparecida de Brito, Elaine Cristina da Silveira, Nicole Cristine Rigonato-Oliveira, Stephanie Souza Soares, Maysa Alves Rodrigues Brandao-Rangel, Clariana Rodrigues Soares, Tawany Gonçalves Santos, Cintia Estefano Alves, Karine Zanella Herculano, Rodolfo Paula Vieira, Adriana Lino-dos-Santos-Franco, Regiane Albertini, Flavio Aimbire, Ana Paula de OliveiraAbstractIdiopathic pulmonary fibrosis (IPF) is a progressive and chronic inflammatory disease with a poor prognosis and very few...
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
Authors: Sielski Ł, Sutkowy P, Katarzyna PO, Woźniak A, Skopkowska A, Woźniak B, Czuczejko J Abstract The aim of the study was to assess the effect of one session of high-intensity laser therapy (HILT) on the levels of selected oxidative stress parameters, lysosomal hydrolases, and anti-inflammatory serine protease inhibitor in the peripheral blood of amateur athletes with torn or pulled tendons of the ankle or the knee joint. The group of injured athletes comprised 16 males and females aged 16.3 ± 1.3 years, while the control group of 14 healthy, noninjured amateur athletes of both sexes (controls; age 1...
Source: The Chinese Journal of Physiology - Category: Physiology Tags: Chin J Physiol Source Type: research
In this study, we quantified the effects of oxytocin or LLLT alone and the combination of oxytocin and LLLT on cortical excitation induced by electrical stimulation of the dental pulp using optical imaging with a voltage-sensitive dye in the neuropathic pain model with partial ligation of the infraorbital nerve (pl-ION). We applied oxytocin (OXT, 0.5 μmol) to the rat once on the day of pl-ION locally to the injured nerve. LLLT using a diode laser (810 nm, 0.1 W, 500 sec, continuous mode) was performed daily via the skin to the injured nerve from the day of pl-ION to 2 days after pl-ION. Cortical responses to electrical ...
Source: Brain Research - Category: Neurology Authors: Tags: Brain Res Source Type: research
Abstract Excessive circulating free fatty acids (FFA) cause insulin resistance in peripheral tissues by inhibiting the proximal insulin signaling pathway. White adipose tissue (WAT) is a primary source of FFA generation and release through triglyceride (TG) hydrolysis. Thus, reducing excessive lipolysis in adipocytes ameliorates whole-body insulin resistance in type 2 diabetes. Here, we found that a noninvasive photobiomodulation therapy (PBMT), decreased FFA generation and release in WATs from high-fat diet (HFD)-fed mice and diabetic db/db mice. Meanwhile, plasma FFA and TG levels were reduced in two mouse model...
Source: Cellular Signalling - Category: Cytology Authors: Tags: Cell Signal Source Type: research
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