AI could help diagnose dogs suffering from chronic pain and Chiari-like malformation

(University of Surrey) A new artificial intelligence (AI) technique developed by the University of Surrey could eventually help veterinarians quickly identify Cavalier King Charles Spaniel (CKCS) dogs with a chronic disease that causes crippling pain. The same technique identified unique biomarkers which inspired further research into the facial changes in dogs affected by Chiari-like malformation (CM).
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news

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ConclusionThe application of additional tactile cues using low thickness placed under the toes could contribute to change postural control and may have therapeutic benefits in the management of patients with chronic pain syndromes. This brings new perspectives also in the management of athletes to prevent injury risk and optimize performance.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
ConclusionThe patient started treatment using B12 vitamin, thiamine, and physical therapy. Currently, despite reported balance improvement, he needs ambulation support. He features nystagmus, bilateral dysmetria, mild dysdiadochokinesia, continuous tinnitus in his left ear, blurred vision, and neck pain while moving it.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
ConclusionsAthletes with CLBP had poorer postural control than healthy athletes. Athletes with CLBP obtained specific cut-off scores on COP values for early detection of the effects of low back pain on balance.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
Conclusion and discussionThe application of additional tactile cues using low thickness placed under the toes could contribute to change postural control and may have therapeutic benefits in the management of patients with chronic pain syndromes. This brings new perspectives too in the management of athletes to prevent injury risk and optimize performance.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
AbstractInjury typically results in the development of neuropathic pain, but the pain normally decreases and disappears in paralleled with wound healing. The pain results from cells resident at, and recruited to, the injury site releasing pro-inflammatory cytokines and other mediators leading to the development of pro-inflammatory environment and causing nociceptive neurons to develop chronic ectopic electrical activity, which underlies neuropathic pain. The pain decreases as some of the cells that induce pro-inflammation, changing their phenotype leading to the blocking the release of pro-inflammatory mediators while rele...
Source: Molecular Neurobiology - Category: Neurology Source Type: research
AbstractThe innervation of the long head of the biceps tendon (LHBT) is not sufficiently documented. This is a drawback since pathologies of the LHBT are a major source of shoulder pain. Thus, the study aimed to characterize structurally and molecularly nervous elements of the LHBT. The proximal part of 11 LHBTs was harvested intraoperatively. There were 8 female and 3 male specimens. Age ranged from 66 to 86  years. For structural analyses, nervous elements were viewed in the transmission electron microscope. For molecular characterization, we used general neuronal markers including antibodies against neurofilament a...
Source: Cell and Tissue Research - Category: Cytology Source Type: research
Opioid withdrawal is one of the more uncomfortable parts of treatment, but it is one of the most important. There are many signs of opioid withdrawal, the length and severity of which can vary from person to person. However, each detox experience almost always includes strong cravings. Symptoms can be mild, such as sweating and yawning, while others can become more serious, like severe anxiety and depression. Opioid withdrawal can look like a scary experience; one that could deter people from getting the help they need. The good news is that it doesn’t need to be fought alone, and there are resources available to ma...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Recovery Detox Resources for Alcohol and Drugs/Opiates drug detox medical detox medicated-assisted detox opioid opioids prescription drug detox withdrawal withdrawal symptoms Source Type: blogs
Study Design. Cross-sectional study. Objective. The aim of this study was to study the personal and societal impact of low back pain (LBP) in patients admitted to a multidisciplinary spine center. Summary of Background Data. The socioeconomic burden of LBP is very high. A minority of patients visit secondary or tertiary care because of severe and long-lasting complaints. This subgroup may account for a major part of disability and costs, yet could potentially gain most from treatment. Currently, little is known about the personal and societal burden in patients with chronic complex LBP visiting secondary/tertiary c...
Source: Spine - Category: Orthopaedics Tags: EPIDEMIOLOGY Source Type: research
Study Design. This is an observational cohort study. Objective. The aim of this study was to compare the effectiveness of PT to an interdisciplinary treatment approach in patients with chronic low back pain (CLBP). Summary of Background Data. CLBP is a costly and potentially disabling condition. Physical therapy (PT), cognitive behavioral therapy, and interdisciplinary pain programs (IPPs) are superior to usual care. Empirical evidence is lacking to clearly support one treatment approach over another in patients with CLBP. Methods. One hundred seventeen adult patients who completed an IPP for individuals with &g...
Source: Spine - Category: Orthopaedics Tags: HEALTH SERVICES RESEARCH Source Type: research
ConclusionAs with all human studies, population sampling and study design matter. Heterogeneity of inclusion and diagnostic criteria and selection bias overwhelmingly account for variability in endometriosis prevalence estimated across the literature. Thus, it is difficult to conclude if the lack of observed change in frequency and distributions of endometriosis over the past 30 years is valid.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
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