An Avocado A Day May Keep Bad Cholesterol At Bay

(CBS) – They say “an apple a day keeps the doctor away”, but a new study from Penn State found an avocado a day can keep your cholesterol at bay. Researchers looked at 45 overweight adults over five weeks and found that those who adhered to a moderate-fat diet that included a daily avocado had significantly lower levels of small, dense particles of LDL or “bad” cholesterol, which promote the buildup of plaque in arteries. They also had higher levels of an antioxidant called lutein. More research needs to be done to confirm this finding, but it probably wouldn’t hurt to incorporate more avocados into your diet, not with mayonnaise-laden guacamole, but perhaps as whole grain avocado toast or by adding chopped avocado to a salad.
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Cholesterol Source Type: news

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AbstractAnacetrapib is an inhibitor of cholesteryl ester transfer protein (CETP) previously under development as a lipid ‐modifying agent that reduces LDL‐cholesterol and increases HDL‐cholesterol in hypercholesterolemic patients. Anacetrapib demonstrates a long terminal half‐life and accumulates in adipose tissue, which contributes to a long residence time of anacetrapib. Given our previous report that anacet rapib distributes into the lipid droplet of adipose tissue, we sought to understand whether anacetrapib affected adipose function, using a diet‐induced obese (DIO) mouse model. Following 20 weeks of tr...
Source: Pharmacology Research and Perspectives - Category: Drugs & Pharmacology Authors: Tags: ORIGINAL ARTICLE Source Type: research
ConclusionsDiabetic nephropathy was common among Chinese patients with type 2 diabetes in primary care in Hong Kong. Early identification and control of the modifiable risk factors are of upmost importance in preventing the complication.
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research
In this study, we characterized an existing KO mouse model lacking the functional MARC2 gene and fed a high-fat diet and also performed in vivo and in vitro experiments to characterize reductase activity toward known MARC substrates. MARC2 KO significantly decreased reductase activity toward several N-oxygenated substrates, and for typical MARC substrates, only small residual reductive activity was still detectable in MARC2 KO mice. The residual detected reductase activity in MARC2 KO mice could be explained by MARC1 expression that was hardly unaffected by KO, and we found no evidence of significant activity of other redu...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Metabolism Source Type: research
Publication date: Available online 8 November 2019Source: Food Research InternationalAuthor(s): Tao Wu, Yufang Gao, Junyu Hao, Jieting Geng, Jiaojiao Zhang, Jinjin Yin, Rui Liu, Wenjie Sui, Lingxiao Gong, Min ZhangAbstractThe present study investigated the anti-obesity effects and its mechanism of capsanthin (CAP) in high-fat diet-induced obese C57BL/6J mice. Compared with untreated mice on a high-fat diet for 12 weeks, CAP at 200 mg kg-1 reduced the body weight by 27.5%, significantly reversed glucose tolerance, effectively decreased the serum triglycerides, total cholesterol, low-density lipoprotein cholesterol, and trim...
Source: Food Research International - Category: Food Science Source Type: research
AbstractBackground and objectivesOrlistat which is taken by obese patients may present some therapeutic assistance through its inhibition of lipase activity. Otherwise, a natural lipase inhibitor as cinnamon is widely used traditional medicine to decrease cholesterol and body weight. The current study aimed to investigate the weight management of orlistat in comparison with cinnamon through different obesity related targets.MethodsSubjects were divided into: Group 1: subjects received cinnamon capsules for 60 days. Group 2: subjects were received orlistat twice daily for 30 days, then once daily for another 30 days. Blood ...
Source: Endocrine - Category: Endocrinology Source Type: research
Publication date: Available online 12 November 2019Source: Food BioscienceAuthor(s): Zhihui Yu, Ning Wang, Fang Geng, Meihu MaAbstractObesity induced by consuming a high-fat diet (HFD) is a major risk for nonalcoholic fatty liver disease, which has become a worldwide health problem. To study the effects of high-density lipoproteins of egg yolk (EYHDL) on mice with HFD induced obesity, lipidomic analyses using ultra performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) was done with serum and liver samples on 60 and 100 days. The results showed that EYHDL significantly alleviated mouse obesity by decreasin...
Source: Food Bioscience - Category: Food Science Source Type: research
In recent years, epidemiologists have found that waist circumference is a better measure of the burden of excess visceral fat tissue than body mass index (BMI). Progress towards making better use of this information has been slow, as is usually the case in the world of epidemiology. Visceral fat tissue generates chronic inflammation through a variety of mechanisms, from DNA debris activating the immune system to inappropriate signaling by fat cells to an accelerated pace of generation of senescent cells. Chronic inflammation disrupts function and accelerates the progression of all of the common age-related conditions. Peop...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Consuming a high-fat diet (HFD) is a risk factor for obesity and diabetes; both of these diseases are also associated with systemic inflammation, similar to HIV infection. A HFD induces intestinal dysbiosis and impairs liver function and coagulation, with a potential negative impact on HIV/SIV pathogenesis. We administered a HFD rich in saturated fats and cholesterol to nonpathogenic (African green monkeys) and pathogenic (pigtailed macaques) SIV hosts. The HFD had a negative impact on SIV disease progression in both species. Thus, increased cell-associated SIV DNA and RNA occurred in the HFD-receiving nonhuman primates, i...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Conclusion: Middle age group population were worst affected by high blood pressure, high blood sugar, poor body mass index, and poor level of cholesterol. Healthy lifestyle measures might reduce the burden of CVD which could be evaluated in future research.
Source: Indian Journal of Community Medicine - Category: International Medicine & Public Health Authors: Source Type: research
Neither vitamin D3 nor omega-3 fatty acid supplements cut CKD risk in people with type 2 diabetes over five years Related items fromOnMedica UK research reveals racial inequalities in diabetes care Statins of small and uncertain benefit in primary prevention Should we recognise obesity as a disease? Sugar not saturated fat is the major issue for CVD WHO dietary fat guidance fails to consider crucial evidence
Source: OnMedica Latest News - Category: UK Health Source Type: news
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