Safety of Food Oral Immunotherapy

Oral immunotherapy (OIT) for food allergy entails a risk of adverse reactions, including anaphylaxis. This safety concern is the major barrier for OIT to become a therapeutic option in clinical practice. The high heterogeneity in safety reporting of OIT studies prevents setting the safety profile accurately. An international consensus is needed to facilitate the analysis of large pooled clinical data with homogeneous safety reporting, that together with integrated omics, and patients/families ’ opinions, may help stratify the patients’ risk and needs, and help developing safe(r) individualized care pathways. This will give OIT the right place in the food allergy therapy.

Source: Immunology and Allergy Clinics of North America - November 5, 2019 Category: Allergy & Immunology Authors: Sonia V ázquez-Cortés, Paloma Jaqueti, Stefania Arasi, Adrianna Machinena, Montserrat Alvaro-Lozano, Montserrat Fernández-Rivas Source Type: research