Retinoic acid regulates olfactory progenitor cell fate and differentiation
Conclusions:
Our data show that retinoic acid is not a simple placodal inductive signal, but rather controls olfactory neuronal production by regulating the fate of olfactory progenitor cells. Retinaldehyde dehydrogenase 3 (RALDH3) is the key enzyme required to generate retinoic acid within the olfactory epithelium.
Source: Neural Development - Category: Neurology Authors: Marie PaschakiLaura CammasYuko MutaYoko MatsuokaSiu-Shan MakMonika Rataj-BaniowskaValérie FraulobPascal DolléRaj Ladher Source Type: research