How many STR markers are enough?

The knowledge of relatedness between individuals is central to many studies in population ´s genetics. To obtain estimates of relatedness with sufficient accuracy, the number of polymorphic markers and the number of alleles per marker is a crucial factor. Because of their allelic diversity, microsatellites, also known as short tandem repeats (STRs), are often recognized as the most effi cient genetic markers (Lynch and Ritland 1999). The aim of our study was to examine the ability of 15 and 22 STR markers included in the Powerplex16 and Powerplex Fusion Kits to detect biological kinship, even in presence of presumptive mutations.
Source: Forensic Science International: Genetics Supplement Series - Category: Forensic Medicine Authors: Source Type: research