Alive but not the same: B.C. woman survives overdose but left with brain damage

Amanda Wright's fentantyl overdose didn't kill her but left her with permanent brain damage, making her one of an unknown number of Canadians, for which there are no concrete statistics, who will require costly care for the rest of their lives.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/British Columbia Source Type: news

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Authors: Baldessarini RJ Abstract Suicide and suicide attempts have become more prevalent in recent years, with notable increases in the US in all age groups and geographic locations. Risk of suicide is particularly high among patients diagnosed with bipolar disorder or severe depression, especially when associated with mixed features or agitation, or with co-occurring substance abuse. Factors contributing to such risk include relative social and geographic isolation and low access to sources of support or clinical care. In addition, unemployment, poverty, demoralisation and opioid abuse have been identified as imp...
Source: Epidemiology and Psychiatric Sciences - Category: Psychiatry Tags: Epidemiol Psychiatr Sci Source Type: research
New research in Ohio links increasing presence of prescription painkillers fentanyl and carfentanil in drug seizures by law enforcement with a rise in opioid-overdose deaths in the state.
Source: Health News - - Category: Consumer Health News Source Type: news
Publication date: Available online 6 November 2019Source: Journal of Pharmaceutical AnalysisAuthor(s): Ningning Zheng, Yu Gu, Ying Hong, Lili Sheng, Linlin Chen, Feng Zhang, Zimiao Weng, Weidong Zhang, Zean Zhang, Wei Jia, Houkai LiAbstractLiver injury caused by acetaminophen (AP) overdose is a leading public health problem. Although AP-induced liver injury is well recognized as the formation of N-acetyl-p-benzoquinone (NAPQI), a toxic metabolite of AP, resulting in cell damage, emerging evidence indicates that AP-induced liver injury is also associated with gut microbiota. However, the gut microbiota-involved mechanism re...
Source: Journal of Pharmaceutical Analysis - Category: Drugs & Pharmacology Source Type: research
(Natural News) For the first time in 30 years the number of drug overdose deaths went down for the first time in 2018. (Article by Jim Hoft republished from President Trump has done more than ANY PRESIDENT IN HISTORY to stem the flow of illegal drugs into the United States. President Trump has done more than...
Source: - Category: Consumer Health News Source Type: news
A pilot scheme that will provide the overdose reversal medicine, naloxone, to those who need it on the streets could be extended across the UK.
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
ConclusionsWe report single or repetitive exposure to several fentanyls using hair testing. To our knowledge, this is the first demonstration of 3-fluorofentanyl and methoxyacetylfentanyl in hair samples collected from an authentic abuser.
Source: Forensic Toxicology - Category: Forensic Medicine Source Type: research
This study explores the epidemiology of pedestrian fatalities in Georgia over a 10-year period with an emphasis on reported substance use among cases. The study employed 10-year data from the Fatality Analysis Reporting System (FARS) administered by the National Highway Traffic Safety Administration. Descriptive methods were used to explore drug screens by person, place, and time. We also examined trends in total drug screens over the examination period. Between 2007 and 2016, 1781 pedestrian crashes were reported to FARS; the fatality rate for this period was 94.5%. Of these, most were male with Blacks and Whites equally ...
Source: Accident Analysis and Prevention - Category: Accident Prevention Source Type: research
Publication date: Available online 6 November 2019Source: Preventive MedicineAuthor(s): Shanthi Krishnaswami, Sutapa Mukhopadhyay, Melissa McPheeters, Sarah J. NechutaAbstractWe performed a statewide evaluation of prescribing patterns of controlled substances (CS) before and after an overdose, using Tennessee's Hospital Discharge Data System and the Controlled Substance Monitoring Database (CSMD). Adults' first non-fatal overdose discharges either from the emergency department (ED) or inpatient (IP) stay occurring between 2013 and 2016 were linked to prescriptions in the CSMD. The difference in the proportion of patients f...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
If investigators can identify the neurologic mechanism of opioid-induced respiratory depression, they might be able to develop an analgesic without the deadly adverse effect.Medscape Medical News
Source: Medscape General Surgery Headlines - Category: Surgery Tags: Pulmonary Medicine News Source Type: news
Authors: Ettienne EB, Ofoegbu A, Maneno MK, Briggs J, Ezeude G, Williams S, Walker C, Chapman E Abstract Opioid use disorder (OUD) constitutes a significant public health burden as opioid overdose deaths have continued to rise in the United States. Although treatment modalities are available to manage OUD, some patients experience challenges achieving their OUD management goals. Some of these challenges may be attributable to inherited genetic variations, or polymorphisms, on the genes that code for proteins impacting the pharmacokinetics or pharmacodynamics of medications used in OUD management. Clinical pharmacog...
Source: Journal of the National Medical Association - Category: General Medicine Tags: J Natl Med Assoc Source Type: research
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