Mechanisms of kidney disease in Sneddon's syndrome: Case report and literature review 
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We report a case of Sneddon's syndrome with chronic kidney disease, associated with features of endarteritis obliterans in the skin and the kidney. The clinical presentation of our patient is compared to previously reported cases of Sneddon's syndrome with biopsy-proven kidney disease. We also discuss the differential diagnosis, pathophysiological mechanisms, relationship with antiphospholipid syndrome, and management of patients with Sneddon's syndrome and kidney disease. This clinical observation supports the systemic nature of Sneddon's syndrome and provides insights into the mechanisms by which this rare but probably underdiagnosed disease alters kidney function.
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PMID: 31661059 [PubMed - as supplied by publisher]

Source: Clinical Nephrology - October 28, 2019 Category: Urology & Nephrology Authors: Ghislain L, Aydin S, Marot L, Demoulin N, Morelle J Tags: Clin Nephrol Source Type: research