Measurement of Thromboxane Biosynthesis in Health and Disease

This article reviews the main findings of four decades of clinical investigation based on these analytical approaches, focusing on the measurement of TXA2 metabolites to characterize the pathophysiologic role of transiently or persistently enhanced platelet activation and to describe the clinical pharmacology of COX-1 inhibition in health and disease.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research