miRNA-103 promotes chondrocyte apoptosis by down-regulation of Sphingosine kinase-1 and ameliorates PI3K/AKT pathway in osteoarthritis.

CONCLUSIONS: Our studies suggest that miRNA-103 contributes to chondrocyte apoptosis, promoting OA progression by down-regulation of PI3K/AKT pathway through the reduction in SPHK1 activity. PMID: 31652455 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31652455?dopt=Abstract

Source: Bioscience Reports - October 29, 2019 Category: Biomedical Science Authors: Li F, Yao J, Hao Q, Duan Z Tags: Biosci Rep Source Type: research

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