Pennsylvania girl who got lung transplants recovering from more surgery
(Reuters) - A 10-year-old Pennsylvania girl with cystic fibrosis who sparked a national debate about child access to organ donations that led to two lung transplant operations was in recovery on Tuesday after surgery to repair her diaphragm, her family said.
Health ministers call on company to lower price of cystic fibrosis drug Orkambi so the NHS can afford it.
Michele Marangi, Giuseppa Pistritto
We report the results of an observational study investigating its effects in CF patients with non-G551D gating mutations.
Antibiotic eradication treatment is the standard-of-care for cystic fibrosis (CF) patients with early Pseudomonas aeruginosa (Pa)-infection; however, evidence from placebo-controlled trials is limited.
Therapies targeting certain CFTR mutants have been approved, yet variations in clinical response highlight the need for in-vitro and genetic tools that predict patient-specific clinical outcomes. Toward this goal, the CF Canada-Sick Kids Program in Individual CF Therapy (CFIT) is generating a “first of its kind”, comprehensive resource containing patient-specific cell cultures and data from 100 CF individuals that will enable modeling of therapeutic responses.
It was back in the 1960s, before computers and the internet, when the power of collecting data on individuals with cystic fibrosis (CF) was first recognized. At that time, CF was almost exclusively a pediatric disease; however, with no national database little was known about the characteristics and survival of those living with the disease. In an effort to better understand the CF population, Dr. Warren Warwick was given a grant to collect statistics from several CF centers in the US. From these data Dr.
A research session co-hosted by the JCF and The Lancet Respiratory Medicine is scheduled for 7th June 2018 at the European Cystic Fibrosis Society conference in Belgrade, Serbia. The session will describe how these journals operate and disseminate the latest findings.
Patients with cystic fibrosis (CF) who experience acute declines in percent predicted FEV1 (ppFEV1 decreased ≥10% relative to baseline) are often not treated with antibiotics for pulmonary exacerbations (PEx), whereas other patients are treated even when they have not experienced a decline in lung function.
Cystic fibrosis (CF) is the most common life-limiting autosomal recessive inherited disease in white populations; it affects approximately 70,000 children and adults worldwide, with a rate of one in 2500 newborns in the UK. It was once considered a childhood disease, but with improvements in diagnosis and treatments, many people with CF are living well into adulthood. In 2016, data from the UK Cystic Fibrosis National Registry reported a median predicted survival of 47 years.