Classifying the antibody-negative NMO syndromes: Clinical, imaging, and metabolomic modeling

Conclusions
PCA identifies 3 phenotypic subgroups within antibody-negative patients and that the metabolite discriminators of RRMS and Ab-NMOSD suggest that these groupings have some pathogenic meaning. Thus, the identified clinico-radiologic discriminators may provide useful diagnostic clues when seeing antibody-negative patients in the clinic.

Source: Neurology Neuroimmunology and Neuroinflammation - October 27, 2019 Category: Neurology Authors: Yeo, T., Probert, F., Jurynczyk, M., Sealey, M., Cavey, A., Claridge, T. D. W., Woodhall, M., Waters, P., Leite, M. I., Anthony, D. C., Palace, J. Tags: Multiple sclerosis, Devic's syndrome Article Source Type: research