Treatment of non-obstructive, non-struvite urolithiasis is effective in treatment of recurrent urinary tract infections

PurposeAbstractTo determine if treatment of non-obstructing urolithiasis is effective in management of recurrent UTI.Materials and methodsA retrospective review was performed of patients undergoing elective management of non-struvite upper tract urinary calculi with recurrent UTI from 2009 to 2016. Recurrent UTI was defined at  ≥ 3 UTI in 12 months, with symptoms and documented urine culture. Preoperative CT was performed in all patients to determine stone burden. All patients had postoperative imaging and ≥ 12 months of follow-up. Pre- and postoperative variables were between patients who had recurrent UTI after treatment versus those who did not.Results46 patients met inclusion criteria. 42 (91.3%) were female. Median age was 63.7  years (IQR 49.1, 73.4) and median total stone burden was 20 mm (IQR 14–35). Within the cohort, 20 (43.5%) underwent ureteroscopy only, 26 (56.5%) underwent PCNL ± URS, and none underwent ESWL. Median postoperative follow-up was 2.9 years (IQR 2.0, 4.3). Only five patients (10.9%) had recu rrent UTI after treatment. 80% were with the preoperative pathogen. The presence of residual stone was an independent risk factor for recurrent UTI after treatment (p 
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research

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Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
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