Using cross-linked hyaluronic acid gel to prevent postoperative lumbar epidural space adhesion: in vitro and in vivo studies

ConclusionsThese results indicate that cross-linked hyaluronic acid gel can prevent epidural adhesion by inhibiting inflammatory factors, such as IL-6, and downregulating TGF β1 and COL1A1 mRNA expression.Graphic abstractThese slides can be retrieved under Electronic Supplementary Material.

http://link.springer.com/10.1007/s00586-019-06193-w

Source: European Spine Journal - October 18, 2019 Category: Orthopaedics Source Type: research