Impact and Interaction of Low Estimated GFR and B Vitamin Therapy on Prognosis Among Ischemic Stroke Patients: The Vitamin Intervention for Stroke Prevention (VISP) Trial

The objective of this study was to conduct a secondary analysis based on the Vitamin Intervention for Stroke Prevention (VISP) trial to clarify these issues. Study Design: In the VISP trial, patients with a prior ischemic stroke were randomly assigned to receive the high- or low-dose B vitamin therapy. The trial did not find a difference between randomly assigned groups. The present study is a secondary analysis of the VISP trial. Setting & Participants: We analyzed the database of a multicenter trial comprising 3,673 patients with recent ischemic stroke who were followed up for 2 years. Predictor: We subdivided the cohort based on eGFR into 6 groups (≥105, 90-104, 75-89, 60-74, 45-59, and
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Authors: Tags: Pathogenesis and Treatment of Kidney Disease Source Type: research