Prediction of Bone Metastasis in Inflammatory Breast Cancer Using a Markov Chain Model

Conclusion.Metastatic patterns of spread differ between patients with IBC and non‐IBC. Selection of patients with IBC with known liver, chest wall, and/or lung metastasis would create a population in whom to investigate effective methods for preventing future bone metastasis.Implications for Practice.This study demonstrated that the patterns of metastasis leading to and following bone metastasis differ significantly between patients with inflammatory breast cancer (IBC) and those with non‐IBC. Patients with IBC had a progression pattern that tended toward the development of bone metastasis if they had previously developed metastases in the liver, chest wall, and lung, rather than in other sites. Selection of patients with IBC with known liver, chest wall, and/or lung metastasis would create a population in whom to investigate effective methods for preventing future bone metastasis.

Source: The Oncologist - October 15, 2019 Category: Cancer & Oncology Authors: Takeo Fujii, Jeremy Mason, Angela Chen, Peter Kuhn, Wendy A. Woodward, Debu Tripathy, Paul K. Newton, Naoto T. Ueno Tags: Breast Cancer Source Type: research