Otitis Media With Effusion Caused by a Parapharyngeal Tumor Showing Normal Nasopharyngeal Findings.

The objective of this study is to evaluate otitis media with effusion (OME) among patients with parapharyngeal tumor. We have experienced 82 parapharyngeal tumor cases and encountered 14 patients complaining of hearing loss due to OME as the initial symptom. These patients showed normal nasopharyngeal findings and the presence of tumor had been detected long time after the beginning of their hearing symptoms (4 months to 13 years: median 2.5 years). Six patients had undergone ventilation tube insertion on the affected ear, which may lead to delay in diagnosis. Pathological examination was performed in 76 of 82 patients. Among these 76 patients, 13 showed OME. Seven patients had malignant lesions, whereas 6 had benign lesions. Therefore, malignant lesions are prone to occur with OME and its relative risk was 2.26 (95% confidence intervals, 1.16-4.42). This difference was statistically significant (P = .044, Fisher test). Otitis media with effusion is a very common disease and is well-known as a primary symptom of nasopharyngeal carcinoma. Therefore, nasopharyngeal observation is necessary for patients with intractable middle ear effusion. However, present 14 patients with OME showed normal nasopharyngeal findings and finally found after an imaging study. From our data, OME is an important but go-by symptom of parapharyngeal tumors. Imaging studies are potently useful for such patients with intractable OME. PMID: 31608684 [PubMed - as supplied by publisher]
Source: Ear, Nose and Throat Journal - Category: ENT & OMF Authors: Tags: Ear Nose Throat J Source Type: research

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This study examined the long-term sequelae of children and adolescent nasopharyngeal carcinoma (NPC) survivors after radiotherapy. Comparing with convention radiotherapy treatment (CRT), intensity-modulated radiotherapy treatment (IMRT) can potentially ameliorate xerostomia, dysphagia and otitis media in survivors. Besides, patients younger than 10 years old had a higher cumulative incidence (CI) of blurred vision. Moreover, a dose of more than 72 Gray (Gy) to primary tumor increased the CI of hearing loss, lalopathy and cranial nerve injury.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Clinical Investigation Source Type: research
Conclusions: ORNTB is a rare complication of radiotherapy that may present years after initial radiation exposure. Management should be aimed at relief of presenting symptoms and treatment of ORNTB associated complications. Both conservative and surgical measures may adequately control the disease process and symptomatology; however, randomized controlled studies comparing treatments would serve to further corroborate these findings.
Source: Otology and Neurotology - Category: ENT & OMF Tags: Tumors of the Ear and Cranial Base Source Type: research
We report a case of a diabetic man who presented with repeating Gradenigo's syndrome symptoms due to NPC.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Source Type: research
Abstract BackgroundThe purpose of this study was to investigate the association between isolated serous otitis media (SOM) and/or conductive hearing loss (CHL) and nasopharyngeal carcinoma (NPC) in a low‐to‐intermediate endemic area. MethodsMedical records of all adult patients (≥17 years) with SOM/CHL who underwent endoscopic‐guided nasopharyngeal biopsy to exclude NPC during a 10‐year period were reviewed. Statistical analyses were conducted to identify significant predictors for NPC. ResultsA total of 195 patients were included (121/195; 62.1% men), among whom 169 (86.7%) presented with isolated SOM/CHL. Over...
Source: Head and Neck - Category: ENT & OMF Authors: Tags: ORIGINAL ARTICLE Source Type: research
We report a rare case of localized nasopharyngeal amyloidosis. Diagnoses: The initial chief complaint of this patient was frequent epistaxis and right aural fullness. The initial diagnosis was nasopharyngeal tumor. Interventions: There is no universally effective medical treatment for nasopharyngeal amyloidosis but surgery can be an option. We performed careful observation with regular follow-up by nasopharyngoscopy and radiologic study. Outcomes: The patient reported no further complaints at 1-year follow-up and the lesion from nasopharyngeal amyloidosis was still present. Lessons: Although it is rare, nasopharyngeal ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Authors: Simo R, Robinson M, Lei M, Sibtain A, Hickey S Abstract This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. Although much commoner in the eastern hemisphere, with an age-standardised incidence rate of 0.39 per 100 000 population, cancers of the nasopharynx form one of the rarer subsites in the head and neck.1 This paper provides recommendations on the work up and management of nasopharyngeal cancer based on the existing evidence base for this condition. Recommendations • Patients with nasopharyngeal carcinoma (NPC) shou...
Source: Journal of Laryngology and Otology - Category: ENT & OMF Tags: J Laryngol Otol Source Type: research
Publication date: Available online 10 November 2016 Source:Egyptian Journal of Ear, Nose, Throat and Allied Sciences Author(s): N. Maithrea, S. Periyathamby, Irfan Mohamad Nasopharyngeal carcinoma (NPC) has a diverse incidence pattern but remains a rare tumour in the pediatric age group. Childhood nasopharyngeal carcinoma usually presents in the second decade of life. Paediatric NPC cases present a diagnostic challenge due to the high prevalence of common NPC presenting symptoms of nasal obstruction, serous otitis media and hearing problems among children. Furthermore, adenoid tissue is most often present, and a biopsy in...
Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences - Category: ENT & OMF Source Type: research
CONCLUSION: There is now a body of evidence specifically related to the aetiology and pathology of otitis media with effusion in adult life. However, further research is required to fill in the gaps in our knowledge and understanding of this condition. PMID: 26976514 [PubMed - as supplied by publisher]
Source: Journal of Laryngology and Otology - Category: ENT & OMF Tags: J Laryngol Otol Source Type: research
This study aimed to investigate the occurrences of post-irradiation chronic suppurative otitis media (CSOM), otitis media with effusion (OME), chronic rhinosinusitis (CRS), and their interrelationship in nasopharyngeal carcinoma (NPC) patients treated by intensity-modulated radiotherapy (IMRT). A retrospective review of medical records and magnetic resonance imaging for NPC patients across a 5-year follow-up was conducted. Rhinosinusitis was diagnosed and staged by Lund–Mackay system. A total of 102 patients were enrolled in the study. On the 5th year following IMRT, 8 patients (7.8 %), 30 patients (29.4 %)...
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research
CONCLUSION: For NPC patients treated with IMRT and chemotherapy, the incidence of treatment-related SNHL was associated with CCD, D0.1ml of cochlea, and SOM. PMID: 26692526 [PubMed]
Source: Translational Oncology - Category: Cancer & Oncology Authors: Tags: Transl Oncol Source Type: research
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