Efficacy, safety, and mechanistic insights of cotadutide a dual receptor glucagon-like peptide-1 and glucagon agonist.

CONCLUSION: These results suggest that the glucose-lowering effects of cotadutide are mediated by enhanced insulin secretion and delayed gastric emptying.
PMID: 31608926 [PubMed - as supplied by publisher]

Source: The Journal of Clinical Endocrinology and Metabolism - October 13, 2019 Category: Endocrinology Authors: Parker VER, Robertson D, Wang T, Hornigold DC, Petrone M, Cooper AT, Posch MG, Heise T, Plum-Moerschel L, Heike S, Klaus B, Ambery PD, Meier JJ, Hirshberg B Tags: J Clin Endocrinol Metab Source Type: research