GSE128136 Full-length transcriptome reconstruction reveals large diversity of RNA isoforms and open reading frames in rat hippocampus

Contributors : Xi Wang ; Jingyi Hou ; Claudia Quedenau ; Wei ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusWe developed a hybrid-sequencing workflow, combining next-generation and third-generation sequencing, to reconstruct full-length transcriptomes. Integrating with polysome profiling and ribosome footprinting data, we predicted isoform –specific translational status and reconstructed ORFeome. Moreover, we identified isoforms with specific subcellular localization pattern in neurons.

Source: GEO: Gene Expression Omnibus - October 14, 2019 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Rattus norvegicus Source Type: research