Saccadic Eye Movements in Young-Onset Parkinson ’s Disease - A BOLD fMRI Study

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Source: Neuro-Ophthalmology - Category: Opthalmology Authors: Source Type: research

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Synaptotagmin12 (SYT12) has been well characterized as the regulator of transmitter release in the nervous system, however the relevance and molecular mechanisms of SYT12 in oral squamous cell carcinoma (OSCC) are not understood. In the current study, we investigated the expression of SYT12 and its molecular biological functions in OSCC by quantitative reverse transcriptase polymerase chain reaction, immunoblot analysis, and immunohistochemistry. SYT12 were up-regulated significantly in OSCC-derived cell lines and primary OSCC tissue compared with the normal counterparts (P
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research
In conclusion, the expression of dopaminergic neuron protective protein mRNAs in hDPSCs was increased by photobiomodulation in defined conditions. However, the cells were not able to differentiate into functional dopaminergic neurons either in control or in photobiomodulated groups that are prone to cell death and exhibit immature dopaminergic neuron characteristics.
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
Falling is common among people with Parkinson's disease (PD). Because of a common amnesia for falls, capturing falls in real-life is challenging. Despite this challenge, we estimate that about 70% of PD patients experience at least one fall per year, w...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
INTRODUCTION: Falls are common among persons with Parkinson's disease (PD). On the other hand, predicting falls is complex as there are both generic and PD-specific contributors. In particular, the role of non-motor symptoms has been less studied. ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
OBJECTIVE: to develop the gerontological nursing care process among the elderly with Parkinson's disease, aiming at the promotion of health through the creation of gerontotechnologies for fall prevention. METHOD: Convergent Care Research was used a...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Authors: Mulak A Abstract Introduction: A growing body of evidence indicates that neuroendocrine interactions may occur at all levels of the brain-gut-microbiota axis, which is directly involved in the pathogenesis of Parkinson's disease (PD).Areas covered: The review presents some current and emerging concepts regarding the organization and functioning of the neuroendocrine system as well as the role of neuroendocrine disturbances in the pathophysiology and symptomatology of PD. The concept of the brain-gut-microbiota triad interactions in the neuroendocrine system and PD is proposed. In PD, dysregulation of the main...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research
ConclusionsOur findings contribute to reveal that the relationship between height and weight is strongly related to frontal cognitive dysfunctions in PD patients.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Corrigendum to "Five-Year Clinical Outcomes of Local versus General Anesthesia Deep Brain Stimulation for Parkinson's Disease". Parkinsons Dis. 2019;2019:2654204 Authors: Tsai ST, Chen TY, Lin SH, Chen SY Abstract [This corrects the article DOI: 10.1155/2019/5676345.]. PMID: 31827761 [PubMed - in process]
Source: Parkinsons Disease - Category: Neurology Tags: Parkinsons Dis Source Type: research
Conditions:   Freezing of Gait;   Parkinson Disease Intervention:   Device: Neuro Omega Sponsor:   Chang Gung Memorial Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
FRIDAY, Dec. 13, 2019 -- Exposure to certain types of oral antibiotics may be associated with an elevated risk for Parkinson disease (PD), according to a study published online Nov. 18 in Movement Disorders. Tuomas H. Mertsalmi, M.D., from...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
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