Randomized Phase II Study of the Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Cetuximab With Cisplatin Versus Cisplatin Alone in Patients With Metastatic Triple-Negative Breast Cancer.

CONCLUSIONWhile the primary study end point was not met, adding cetuximab to cisplatin doubled the ORR and appeared to prolong PFS and OS, warranting further investigation in mTNBC. PMID: 23733761 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/23733761?dopt=Abstract

Source: Clinical Breast Cancer - June 3, 2013 Category: Cancer & Oncology Authors: Baselga J, Gómez P, Greil R, Braga S, Climent MA, Wardley AM, Kaufman B, Stemmer SM, Pêgo A, Chan A, Goeminne JC, Graas MP, Kennedy MJ, Ciruelos Gil EM, Schneeweiss A, Zubel A, Groos J, Melezínková H, Awada A Tags: J Clin Oncol Source Type: research