Vote Aids Children Under 12 Seeking Lung Transplant

Officials with the Organ Procurement and Transplantation Network voted in an emergency meeting to create a new avenue for children seeking lung transplants.    
Source: NYT Health - Category: Consumer Health News Authors: Tags: Cystic Fibrosis Murnaghan, Sarah Organ Procurement and Transplantation Network Decisions and Verdicts Transplants Sebelius, Kathleen Health and Human Services Department Lungs Acosta, Javier Children and Childhood Source Type: news

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AbstractPurpose of ReviewMycobacterium kansasii is a slow-growing member of the nontuberculous mycobacterial species that manifests clinically with pulmonary, cutaneous, or disseminated forms. Most cases ofM. kansasii infection occur in immunocompromised hosts including HIV/AIDS, solid-organ transplantation, anti-interferon- γ antibody disorder, or among those with pulmonary disorders such as chronic obstructive pulmonary disease or cystic fibrosis. In this review, we aim to discuss relevant literature regarding the clinical manifestations of this infection with a particular emphasis on the clinical spectrum and trea...
Source: Current Tropical Medicine Reports - Category: Tropical Medicine Source Type: research
Abstract Plasmid DNA (pDNA) is an attractive therapeutic biomolecule in several diseases including cancer, AIDS, cystic fibrosis, Parkinson's disease and Alzheimer's disease. Increasing demand for plasmid DNA as a therapeutic biomolecule for transgene expression or vaccine applications necessitate novel approaches to bioprocessing. We previously described the synthesis, characterization and evaluation of aminoglycoside-derived hydrogel microbeads ("Amikabeads") for pDNA binding. Here, we describe the generation and evaluation of novel chemotherapeutic drug-conjugated microbeads for application in pDNA bi...
Source: Biotechnology Journal - Category: Biotechnology Authors: Tags: Biotechnol J Source Type: research
Pseudomonas aeruginosa is the major cause of burn sepsis, and there are several reports about outbreaks of infections by this bacterium in burn centers of different hospitals worldwide [1]. According to the survey conducted by the US National Healthcare Safety (2007), out of approximately 28,000 cases of nosocomial infections from 463 hospitals over a 22 month period, P. aeruginosa was found to be the most frequently occurring pathogen, especially in burn wounds, AIDS and cystic fibrosis patients [2].
Source: Burns : Journal of the International Society for Burn Injuries - Category: Cosmetic Surgery Authors: Source Type: research
Abstract With over 1900 variants reported in the cystic fibrosis transmembrane conductance regulator (CFTR), enhanced understanding of cystic fibrosis (CF) genotype-phenotype correlation represents an important and expanding area of research. The potentiator Ivacaftor has proven an effective treatment for a subset of individuals carrying missense variants, particularly those that impact CFTR gating. Therapeutic efforts have recently focused on correcting the basic defect resulting from the common F508del variant, as well as many less frequent missense alleles. Modest enhancement of F508del-CFTR function has been a...
Source: Current Opinion in Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Opin Pharmacol Source Type: research
Researchers from the University of Massachusetts have developed a protein-based...Read more on AuntMinnie.comRelated Reading: Is ferumoxytol the alternative to gadolinium MRI agents? Glucose-MRI technique at 7T aids tumor evaluation Short breast MRI protocol works for cancer detection Novel MRI scans could aid in cystic fibrosis MRI can replace biopsy for prostate cancer surveillance
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
This article was originally published on Complex Child.  Compiled by Susan Agrawal I’ve been continually surprised by how many people think Medicaid is just for poor families on welfare. Those of us who parent children with complex medical needs know that Medicaid is so much more than that. After all, 72% of Medicaid enrollees are children, people with disabilities, and the elderly, and these groups account for 84% of spending. Medicaid provides vital services for children, including home nursing care and therapies, that are not otherwise covered. In this article, we will share just a few of the children with me...
Source: Disruptive Women in Health Care - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: blogs
CONCLUSIONS: There is a lack of robust evidence for interventions to manage fatigue and/or unintentional weight loss in the advanced stage of progressive illnesses such as advanced cancer, heart failure, lung failure, cystic fibrosis, multiple sclerosis, motor neuron disease, Parkinson's disease, dementia and AIDS. The evidence contained within this overview provides some insight into interventions which may prove of benefit within this population such as exercise, some pharmacological treatments and support for self management.Researchers could improve the methodological quality of future studies by blinding of outcome as...
Source: Cochrane Database of Systematic Reviews - Category: Journals (General) Authors: Tags: Cochrane Database Syst Rev Source Type: research
Abstract Pseudomonas aeruginosa is a common opportunistic human pathogen. It generally attacks immunosuppressed patients like AIDS, cancer, cystic fibrosis, etc. The virulence of P. aeruginosa is mediated by various virulence factors. One of such potential virulence factors is HCN synthesized by HCN synthase enzyme, which is encoded by the hcnABC operon. The expressions of the genes of this operon are regulated by three transcriptional regulators, viz., LasR, ANR, and RhlR. In our previous work, we analyzed the molecular details of the functionalities of LasR. In this work, we focused on ANR. ANR is a regulatory p...
Source: Applied Biochemistry and Biotechnology - Category: Biochemistry Authors: Tags: Appl Biochem Biotechnol Source Type: research
Publication date: Available online 30 August 2016 Source:Genes & Diseases Author(s): Liquan Cai, Alfred L. Fisher, Haochu Huang, Zijian Xie CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology has emerged as a powerful technology for genome editing and is now widely used in basic biomedical research to explore gene function. More recently, this technology has been increasingly applied to the study or treatment of human diseases, including Barth syndrome effects on the heart, Duchenne muscular dystrophy, hemophilia, β-Thalassemia, and cystic fibrosis. CRISPR/Cas9 (CRISPR-associated protein...
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
Marijuana is widely used, especially in adolescents and young adults. In the US, there are about 20 million users (about 7.5% of people aged 12 or older). Marijuana is a mind-altering (psychoactive) drug. Similar to hemp, it comes from the cannabis plant. The plant’s primary drug effects come from the chemical delta-9-tetrahydrocannabinol, or “THC.” Marijuana is smoked, “vaped” (inhaling the vapor), or ingested in foods or teas. Over the last few decades, the concentration of THC in the cannabis plant has been increasing. In addition, the plant extracts are more potent. Short-term effects of m...
Source: New Harvard Health Information - Category: Consumer Health News Authors: Tags: Behavioral Health Brain and cognitive health Drugs and Supplements Pain Management Source Type: news
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