CLCN2 clicks with aldosterone-producing adenomas, too!

CLCN2 clicks with aldosterone-producing adenomas, too!
Eur J Endocrinol. 2019 Nov 01;181(5):C21-C22
Authors: Scholl UI
Abstract
Germline mutations in the chloride channel gene CLCN2 have been described as cause of familial hyperaldosteronism type II. In this issue, Dutta and colleagues in a groundbreaking study identify a somatic (tumor-specific) CLCN2 mutation in an aldosterone-producing adenoma, expanding the disease spectrum associated with CLCN2 mutations.
PMID: 31585437 [PubMed - in process]

Source: European Journal of Endocrinology - October 6, 2019 Category: Endocrinology Authors: Scholl UI Tags: Eur J Endocrinol Source Type: research