Substituted Furanocoumarins as Novel Class of Antibacterial Translation Inhibitors.

CONCLUSION: High antibacterial activity in combination with low cytotoxicity was demonstrated for a series of furanocoumarins. Further optimization of the described structures may result in novel and attractive lead compounds with promising antibacterial efficiency.
PMID: 31573876 [PubMed - in process]

Source: Combinatorial Chemistry and High Throughput Screening - October 2, 2019 Category: Chemistry Authors: Ivanenkov YA, Yamidanov RS, Osterman IA, Sergiev PV, Ayginin AA, Aladinskiy VA, Aladinskaya AV, Terentiev VA, Veselov MS, Skvortsov DA, Komarova KS, Chemeris AV, Zainullina LF, Maximova MA, Zileeva ZR, Vakhitova YV, Baymiev AK, Baymiev AK, Sofronova AA, M Tags: Comb Chem High Throughput Screen Source Type: research