P.20Expanding the myasthenia-myositis association spectrum: clinical, morphological and immunological data form a large case series

Myastenia-inflammatory myopathy (MG-IM) association has been described in less than 50 cases, as isolated reports or in few case series. In most cases, MG and IM onset occur simultaneously even if the overlapping clinical manifestations could lead to delay the diagnosis in the early stage of disease. In these cases, thymic pathology is present in more than 50% of cases. Pathological findings can be consistent of polymyositis (63%), dermatomyositis (25%) or granulomatosis (12%). MSA and muscle MRI involvement have not been systematically investigated.

Source: Neuromuscular Disorders - September 30, 2019 Category: Neurology Authors: M. Garibaldi, L. Fionda, F. Vanoli, L. Leonardi, E. Bucci, S. Morino, G. Merlonghi, M. Lucchini, M. Mirabella, F. Andreetta, E. Pennisi, A. Petrucci, G. Antonini Source Type: research