Pregnancy success and outcomes after uterine fibroid embolization: updated review of published literature.
Pregnancy success and outcomes after uterine fibroid embolization: updated review of published literature. Br J Radiol. 2019 Oct 01;:20190551 Authors: Ludwig P, Huff TJ, Shanahan MM, Stavas JM Abstract Females with symptomatic leiomyomas (fibroids) wishing to maintain fertility are faced with difficult treatment choices. These include uterine fibroid embolization (UFE), myomectomy, hormonal therapy, MRI high intensity focused ultrasound, and myolysis. This review focuses on UFE, one of the most commonly accepted minimally invasive procedural choices among patients with symptomatic fibroids wishing to retain the option of becoming pregnant in the future, and makes comparisons to myomectomy which has historically been the surgical choice for fertility-preserving fibroid treatment. Pubmed and Google Scholar searches using keywords such as: uterine artery embolization, uterine fibroid embolization, pregnancy, complications, infertility were performed between Jan. 1, 2019 and May 10, 2019. Publications were chosen based on their inclusion of information pertaining to fertility or pregnancy after UFE without being limited to single case reports.Randomized controlled trials comparing myomectomy and UFE are limited due to study size and confounding variables, but through registry data and familiarity with referring clinicians, UFE has gained wide acceptance. Healthy pregnancies following UFE have been sporadically reported but the actual fertility rate after UFE...
The paper presents the design and validation of body-conformal active ultrasound patches with integrated imaging and modulation modalities for image-guided neural therapy. A mechanically-flexible linear 64-element array of piezoelectric transducers with a resonance frequency of 5 MHz was designed for nerve localization. A second 8-element array using larger elements was integrated on the wearable probe for low intensity focused ultrasound neuromodulation at a resonance frequency of 1.3 MHz. Full-wave simulations were used to model the flexible arrays and estimate their generated pressure profiles. A focal depth o...
AbstractLeiomyomatosis is a uterine condition that can rarely present with extrauterine involvement. Intravenous and intracardiac extensions are extremely rare presentations and, in these cases, the intra ‐cardiac mass may be confused with a cardiac myxoma and can be associated with pulmonary embolism. Here we report two cases of successful surgically removed intracardiac leiomyomas under cardiopulmonary bypass.
Publication date: Available online 30 March 2020Source: Interdisciplinary NeurosurgeryAuthor(s): Visvanathan Krishnaswamy, Jai Prakash Srinivasan, Abhirama Chandra Gabbita, Sudha Ram
AbstractThe aim of this study was to evaluate the impact of pregestational diabetes mellitus (DM) on fetal cardiac function two-dimensional parameters using spectral and tissue Doppler. Pregnant women between 20 and 36 + 6 weeks gestation were divided into three groups: controls, type I DM, and type II DM. The right ventricle (RV) and left ventricle (LV) annular velocity peaks were measured using spectral (E, A) and tissue (E′, A′, S′) Doppler. The myocardial performance index was calculated as (isovolu metric contraction time [ICT] + isovolumetric relaxation time [IRT])/eject...
British Journal of Cancer, Published online: 31 March 2020; doi:10.1038/s41416-020-0816-8Dose-dense adjuvant chemotherapy in early breast cancer patients: 15-year results of the Phase 3 Mammella InterGruppo (MIG)-1 study
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British Journal of Cancer, Published online: 31 March 2020; doi:10.1038/s41416-020-0819-5Comment on: “Exploring the best treatment options for BRAF-mutant metastatic colon cancer”
British Journal of Cancer, Published online: 31 March 2020; doi:10.1038/s41416-020-0784-zSurvival and disease characteristics of de novo versus recurrent metastatic breast cancer in a cohort of young patients
In April 1999, the British government established a new institute, NICE, to assess the clinical and cost ‐effectiveness of medicines and devices for use by the National Health Service in England. To mark its 21st birthday, NICE's former chair,Michael D. Rawlins, and former chief executive,Andrew Dillon, reflect on the organisation's contributions – plus a few controversies along the way
CONCLUSION: Leiomyoma presence was not associated with increased risk of spontaneous abortion in an analysis of more than 20,000 pregnant women. Failure of prior studies to adjust for confounders may have led to the common clinical belief that leiomyomas are a risk factor for spontaneous abortion. PMID: 29016496 [PubMed - as supplied by publisher]