Epidemiological and Pathological Characterization of Feline Injection Site Sarcomas in Southern Brazil

Publication date: October 2019Source: Journal of Comparative Pathology, Volume 172Author(s): B.S. Cecco, L.C. Henker, C. De Lorenzo, C.I. Schwertz, R.M. Bianchi, F.V.A. da Costa, D. Driemeier, S.P. Pavarini, L. SonneSummaryFeline injection site sarcoma (FISS) is a mesenchymal neoplasm with highly malignant characteristics. These tumours originate in anatomical sites where there has been previous parenteral administration of medicinal substances or implantation of medical devices. The aim of this study was to investigate the epidemiological and pathological features associated with FISS in the southern region of Brazil. The database of the Department of Veterinary Pathology of the Federal University of Rio Grande do Sul was searched for excisional and incisional biopsy samples compatible with FISS submitted between 2007 and 2017. Biopsy reports were reviewed and epidemiological information, including breed, age and sex of affected cats, as well as gross findings including anatomical location and size of the tumour and the presence of tissue invasion, were extracted. Eighty-nine samples were selected based on the established criteria. Most animals were of undefined breed and were female cats with a median age of 10 years. Grossly, 84.8% of the tumours were>2 cm in diameter. Regarding anatomical location, 34.9% of the tumours were located in the subcutaneous tissue of the thoracic wall, 29.2% in the flank, 21.3% in the interscapular region and 14.6% in the limbs. Histologically...
Source: Journal of Comparative Pathology - Category: Pathology Source Type: research