Automated 4-dimensional regional myocardial strain evaluation using cardiac computed tomography

AbstractEvaluation of myocardial regional function is generally performed by visual “eyeballing” which is highly subjective. A robust quantifiable parameter of regional function is required to provide an objective, repeatable and comparable measure of myocardial performance. We aimed to evaluate the clinical utility of novel regional myocardial strain software from cardiac comp uted tomography (CT) datasets. 93 consecutive patients who had undergone retrospectively gated cardiac CT were evaluated by the software, which utilizes a finite element based tracking algorithm through the cardiac cycle. Circumferential (CS), longitudinal (LS) and radial (RS) strains were calculate d for each of 16 myocardial segments and compared to a visual assessment, carried out by an experienced cardiologist on cine movies of standard “echo” views derived from the CT data. A subset of 37 cases was compared to speckle strain by echocardiography. The automated software performed success fully in 93/106 cases, with minimal human interaction. Peak CS, LS and RS all differentiated well between normal, hypokinetic and akinetic segments. Peak strains for akinetic segments were generally post-systolic, peaking at 50 ± 17% of the RR interval compared to 43 ± 9% for normokinetic segments. Using ROC analysis to test the ability to differentiate between normal and abnormal segments, the area under the curve was 0.84 ± 0.01...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research

Related Links:

ConclusionsIn this study, there was no significant enlargement of the orbital rim with increasing age in Koreans. The measurement data in the present study differ from previous studies involving White subjects, which revealed a significant increase in orbital aperture area.
Source: Surgical and Radiologic Anatomy - Category: Anatomy Source Type: research
AbstractObjectivesTo assess the prevalence of dental implant-related perforations of relevant anatomical structures and inadequate spacing between the implant and the adjacent tooth or implant, and their association with anatomical location, implant dimension, thread exposure, and presence of graft, using cone beam computed tomography (CBCT).Materials and methodsCBCT scans of patients with implants were retrospectively assessed regarding the presence of implant-related perforation of adjacent anatomical structures, and inadequate mesial and distal spacing between the implant and the adjacent tooth/implant (i.e.,
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research
Publication date: Available online 18 January 2020Source: Journal of Orthopaedic TranslationAuthor(s): Muzhi Li, Yifu Tang, Can Chen, Jiefu Zhou, Cheng Zheng, Huabin Chen, Hongbin Lu, Jin QuAbstractBackgroundMany orthopedic surgical procedures involve reattachment between tendon and bone. Whether bone–tendon healing is better facilitated by tendon fixation on a bone surface or within a tunnel is unknown. The purpose of this study was to comparatively evaluate the effects of bone surface versus bone trough fixation on bone–tendon healing in a rabbit patella–patellar tendon (PPT) injury model.MethodsThe rab...
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research
ConclusionWhen the cross-link during PSO surgery was positioned two levels away from the PSO site, the risk of rod fracture did not increase.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
CONCLUSIONS: These results provide the first evidence that TAVI may improve cognitive functions associated with increased cerebral perfusion especially in the hippocampus in elderly patients with severe AS. PMID: 31951203 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
This study sought to derive and validate a systematic method enabling AVC quantification using computed tomography angiography (CTA) in patients with AS.Methods134 consecutive patients with AS who underwent both NCCT and CTA were included in the study and sub-divided into derivation (n=71) and validation cohorts (n=63). On NCCT, AVC was quantified using Agatston method utilizing the software developed for semi-automatic assessment of coronary calcium. On CTA, mean contrast attenuation of aorta (AortaHU) and standard deviation (SD) was measured in the region-of-interest at level of sinotubular junction.ResultsUsing an adjus...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsThe performance of the systems proved to be image quality specific, depending on the DVF type and only partially on the platforms. All systems proved to be robust against image artifacts and noise, except the demon-based software.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
Authors: Crapé L, Strubbe B, Cesmeli E, de Clerck F Abstract A 24-year-old male presented with abdominal pain, postprandial vomiting and weight loss. Lab results showed an elevated serum eosinophil count and CT-scan demonstrated a thickened antral, duodenal and jejunal wall. Repetitive endoscopic mucosal biopsies were normal. Work-up of eosinophilia-associated gastro-intestinal disorders excluded secondary causes. Bone marrow showed an elevated eosinophil count without arguments for a primary hypereosinophilic syndrome. Endoscopic ultrasound-guided fine needle biopsy detected a strongly elevated number of eo...
Source: Acta Gastro-Enterologica Belgica - Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research
CONCLUSION: CT is helpful in predicting GIF in patients with AP. PMID: 31950804 [PubMed - in process]
Source: Acta Gastro-Enterologica Belgica - Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research
ConclusionsAn advanced 3-D printing model provides affirmative information related to treatment strategy and is also a prospective tool for better doctor –patient communication regarding the disease.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
More News: Cardiology | Cardiovascular | CT Scan | Heart | Radiology