Incidence of diagnosed type 2 diabetes declining since 2006

'Sensibly optimistic systematic review does not provide definitive evidence that true incidence is falling ’ Related items fromOnMedica Scotland reveals target of halving child obesity by 2030 Obesity as cause of cancer set to overtake smoking Should we recognise obesity as a disease? Type 2 diabetes in 10 times more young people than realised Even athletes can ’t outrun the effects of a bad diet
Source: OnMedica Latest News - Category: UK Health Source Type: news

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The Organisation for Economic Co-operation and Development report said 62 per cent of adults in the UK are overweight, putting them at risk of type 2 diabetes, heart disease, strokes and cancer.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Abstract Protein arginine methyltransferases (PRMTs) are a family of enzymes that catalyze the methylation of arginine residues on target proteins and thus alter the stability, localization, or activity of the substrate. In doing so, PRMTs mediate a variety of intracellular functions that are essential for survival. Additionally, PRMT dysregulation is involved in a number of the most prevalent health disorders, including cancer, neurodegenerative and cardiovascular diseases, as well as in the aging process. Investigations of PRMT biology in skeletal muscle cells began in 2002, and since then these enzymes have eme...
Source: American Journal of Physiology. Endocrinology and Metabolism - Category: Physiology Authors: Tags: Am J Physiol Endocrinol Metab Source Type: research
Publication date: December 2019Source: Biomedicine &Pharmacotherapy, Volume 120Author(s): Babalwa U. Jack, Christiaan J. Malherbe, Mokadi Mamushi, Christo J.F. Muller, Elizabeth Joubert, Johan Louw, Carmen PheifferAbstractObesity is a significant contributor to increased morbidity and premature mortality due to increasing the risk of many chronic metabolic diseases such as type 2 diabetes, cardiovascular disease and certain types of cancer. Lifestyle modifications such as energy restriction and increased physical activity are highly effective first-line treatment strategies used in the management of obesity. However, a...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Abstract Obesity is a significant contributor to increased morbidity and premature mortality due to increasing the risk of many chronic metabolic diseases such as type 2 diabetes, cardiovascular disease and certain types of cancer. Lifestyle modifications such as energy restriction and increased physical activity are highly effective first-line treatment strategies used in the management of obesity. However, adherence to these behavioral changes is poor, with an increased reliance on synthetic drugs, which unfortunately are plagued by adverse effects. The identification of new and safer anti-obesity agents is thus...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research
Publication date: Available online 1 October 2019Source: Food ChemistryAuthor(s): David de Paulo Farias, Iramaia Angélica Neri-Numa, Fábio Fernandes de Araújo, Glaucia Maria PastoreAbstractThe Myrtaceae family is one of the world's leading commercial fruit tree families. Among the 121 genera belonging to this family, the Syzygium, Eugenia and Campomanesia genera are constituted by a wide variety of fruit species with great potential to be explored economically, besides presenting excellent nutritional value and being considered sources of phytochemicals such as phenolic compounds, carotenoids and volat...
Source: Food Chemistry - Category: Food Science Source Type: research
AbstractBackgroundThe android:gynoid percent fat ratio (AGFR) is associated with increased risk of cardiovascular disease and type 2 diabetes in breast cancer survivors (BCS). Exercise reduces fat mass in BCS; however, few studies have focused on AGFR. The study purpose was to examine the effects of a 16-week aerobic and resistance exercise intervention on AGFR among BCS. We assessed whether exercise-induced changes in AGFR were associated with improved insulin resistance.MethodsBCS (Stage I-III) were randomized to exercise (n  = 50) or usual care (n = 50). The thrice weekly 16-week intervention...
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research
Authors: Saitta C, Pollicino T, Raimondo G Abstract Obesity prevalence is rapidly increasing worldwide. It is associated with huge economic and health costs due to its clinical consequences, which includes increased incidence of type 2 diabetes, cardiovascular diseases, and development of different malignancies. In particular, obesity is an independent risk factor for the development of hepatocellular carcinoma (HCC). Indeed, obesity is highly prevalent in patients with non-alcoholic fatty liver disease (NAFLD) that is becoming one of the most frequent causes of liver disease worldwide. NAFLD-related HCC is the mos...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
People with poor lifestyle and obesity are at greater risk of incident T2D – regardless of their genetic risk Related items fromOnMedica Majority of patients ignorant of obesity link to cancer Health system ‘all too often’ lets down people with diabetes Many patients ignore symptoms of diabetes Annual diabetes checks still being missed Tackling obesity ‘must be made a national priority’
Source: OnMedica Latest News - Category: UK Health Source Type: news
We examined human lung tissue from COPD patients and normal control subjects, and found a substantial increase in p16-expressing alveolar cells in COPD patients. Using a transgenic mouse deficient for p16, we demonstrated that lungs of mice lacking p16 were structurally and functionally resistant to CS-induced emphysema due to activation of IGF1/Akt regenerative and protective signaling. Fat Tissue Surrounds Skeletal Muscle to Accelerate Atrophy in Aging and Obesity https://www.fightaging.org/archives/2019/09/fat-tissue-surrounds-skeletal-muscle-to-accelerate-atrophy-in-aging-and-obesity/ Researchers her...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Publication date: Available online 5 September 2019Source: Trends in Food Science &TechnologyAuthor(s): David de Paulo Farias, Fábio Fernandes de Araújo, Iramaia Angélica Neri-Numa, Glaucia Maria PastoreAbstractBackgroundCurrently, there is a growing interest in the identification of new molecules that promote health and exhibit potential for technological applications. Prebiotics are functional ingredients naturally occurring in some plant and animal foods that have received considerable attention from the pharmaceutical and food industries due to their positive health effects. With an increasing ...
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research
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