A pediatric case report of fixed drug eruption related to carmoisine colorant present in paracetamol syrup

George Mathew Panachiyil, Tirin Babu, Juny Sebastian, Narayanappa DoddaiahIndian Journal of Pharmacology 2019 51(4):279-281 Various adverse drug reactions, including hypersensitivity skin reaction after the exposure to carmoisine colorant, have already been reported in the literature. This case report gives the details of a 5-year-old male child with a recurrent fixed drug eruption (FDE) over the neck and trunk after the use of paracetamol syrup containing carmoisine as a colorant. Patch test to the carmoisine colorant in the paracetamol syrup was positive. This case report adds an increased awareness of the probability of allergic skin reaction to carmoisine in a previously sensitized person. The report also emphasizes the necessity to consider artificial dyes in pharmaceutical products as a potential cause for FDE.
Source: Indian Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Source Type: research