The rarity of paralysis following poliovirus infection
After infection with poliovirus, only about 1% of individuals develop paralysis. I have always wondered whether genetic polymorphisms underlie the rarity of this disease outcome. The results of study carried out in Denmark provide the first insights. The study group consisted of 17 individuals who developed poliomyelitis in the pre-vaccine years, 1940-1950, and one who […]
Source: virology blog - Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information genetic susceptibility paralysis poliomyelitis poliovirus single nucleotide polymorphism SNIP viral viruses Source Type: blogs
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