The association between anemia and some aspects of functionality in older adults
Conclusion: The presence of difficulties in chewing and swallowing were associated with higher prevalence of anemia, even after adjustment for other factors, with a dose-response effect, indicating the importance of a multidisciplinary work with older adults.
Publication date: January 2020Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 129, Issue 1Author(s): RAYZA RECHETNICOU, MARIA FERNANDA BARTHOLO SILVA, NATÁLIA SILVA ANDRADE, KAREM LOPEZ ORTEGA, MARINA HELENA CURY GALLOTTINIObjectiveThe life expectancy of people positive for human immunodeficiency virus (HIV) has increased since the advent of combined antiretroviral therapy (CART). There was a decrease in opportunistic infections in this population, but on the other hand, there were side effects to medications and medical conditions related to longevity. The main of this prospective stu...
We report 2 cases of oral squamous cell carcinoma in male patients with FA who underwent hematopoietic stem cell transplantation. Both patients presented with oral lichenoid lesions, compatible with chronic graft vs host disease. In the first case, a 16-year-old patient presented with an extensive infiltrative and necrotic lesion on the border of the tongue.
Fanconi anemia (FA) is a rare autosomal recessive genetic disorder, characterized by congenital malformations of certain organs, thrombocytopenia, and chronic anemia due to the progressive failure of bone marrow, with an elevated risk of infections and bleeding. A 24-year-old male patient with FA was referred to our clinic with a chief complaint of cheek biting and resultant significant bleeding. During clinical evaluation, a traumatic ulcer in the left buccal mucosa was observed with a massive blood clot formed inappropriately along with continuous bleeding.
Fanconi Anemia (FA) is a rare autosomal recessive genetic disorder that can cause bone marrow failure and increased risk for malignancies. Hematopoietic stem cell transplantation (HSCT) in patients with FA also increases the risk of tumors. The following reported case is of a male patient, diagnosed with AF, with a history of HSCT at 4 years of age. At 14 years old, he presented with a painless ulcerated lesion, irregular borders, 3 cm in size, on the right lateral border of the tongue with a 20-day course, associated with a submandibular lymphadenopathy.
An 82-year-old female patient with anemia (hemoglobin 9 g/dL) and a history of alendronate and zolendronic acid use for osteoporosis was referred to our clinic with a chief complaint of pain in the maxilla. During clinical examination, mucosal erythema in the anterior maxilla in a region that had been surgically accessed for the extraction of a tooth 1 year earlier was the only clinical sign compatible with the complaint. Her overall mucosa was pale, associated with her low hemoglobin count. After radiographic evaluation, the alveolar bone that was once circumscribing the extracted tooth had no signs of resorption.
We report 2 cases of patients diagnosed with aplastic anemia that underwent surgical dental procedures. Patient 1, male, 27 years old, 4000 platelets/mm3, needed extraction of the 3 left inferior molars. Patient 2, female, 18 years old, 5000 platelets/mm3, had referred pain in the first left lower molar with the need of extraction.
Fanconi anemia (FA) is a rare autosomal recessive syndrome characterized by bone marrow failure, malformations, and chromosome fragility. Patients who reach adulthood are more likely to develop solid tumors, such as oral squamous cell carcinoma. The survival rate of patients with FA is low, since they present with hematologic complications, septicemia, or malignant neoplasias. The aim of this study is to report 2 cases of female patients with FA at 20 and 34 years of age, both of whom underwent transplantation of hematopoietic stem cells 8 and 17 years ago, respectively, and who developed oral lesions on the tongue and gin...
An 18-year-old white woman was referred to our service with complaint of “ulcerations on the tongue.” The lesions worsened in the last 6 months when the orthodontic appliance was placed. The patient was vegetarian, and she reported a prolonged menstrual period. Oral examination revealed multiple symptomatic ulcerations with irregular shape with pseudomembrane involvi ng the lower lip, tongue, and buccal mucosa bilaterally. Laboratory tests were requested, which showed sickle cell trait of anemia with presence of microcytic red blood cells as well as iron deficiency and ferritin.
Graft-vs-host disease (GVHD) is the main complication of allogeneic hematopoietic stem cells transplantation. A 29-year-old Brazilian man was diagnosed as having severe aplastic anemia and submitted to allogeneic HSCT in October 2013. He developed systemic chronic GVHD, including the oral cavity (lichenoid lesions in right and left buccal mucosa and labial hyperchromia and was treated with mycophenolate mofetil, tacrolimus, cyclosporine, and dexamethasone solution [mouthwash]). Upon stabilization of chronic GVHD in the oral cavity, the patient displayed gingival atrophy and erythema (12-21/33-42) on July 27, 2017.
An 86-year-old man was evaluated complaining a painful lesion situated in the tongue with 45-day duration. Medical history revealed anemia, heart disease, vasculitis, and glomerulitis associated with the previous diagnosis of Wegener granulomatosis. Positive reaction for antineutrophil cytoplasmic autoantibodies (ANCA) was reported. Intraoral examination revealed an asymptomatic ulceration on the dorsum of the tongue surrounded by a whitish area that measures its 2.0 × 1.0 cm in its largest diameters.