The alveolar immune cell landscape is dysregulated in checkpoint inhibitor pneumonitis

CONCLUSION We observe several immune cell subpopulations that are dysregulated in CIP, which may represent possible targets that could lead to therapeutics for this morbid immune-related adverse event.FUNDING NIH, Department of Defense, and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.

Source: Journal of Clinical Investigation - September 5, 2019 Category: Biomedical Science Authors: Karthik Suresh, Jarushka Naidoo, Qiong Zhong, Ye Xiong, Jennifer Mammen, Marcia Villegas de Flores, Laura Cappelli, Aanika Balaji, Tsvi Palmer, Patrick M. Forde, Valsamo Anagnostou, David S. Ettinger, Kristen A. Marrone, Ronan J. Kelly, Christine L. Hann, Source Type: research