A Novel Tissue-Based liver-kidney-on-a-chip can Mimic Liver Tropism of Extracellular Vesicles Derived from Breast Cancer Cells.

CONCLUSIONS: Overall, the tropism of EVs to different organs was reconstituted on the microfluidic model. The liver-kidney-on-a-chip may expand the capabilities of traditional cell culture models and provide a faster alternative to animal models for EV studies. This article is protected by copyright. All rights reserved.
PMID: 31473998 [PubMed - as supplied by publisher]

Source: Biotechnology Journal - August 31, 2019 Category: Biotechnology Authors: Tian H, Pang J, Qin K, Yuan W, Kong J, Ma H, He J, Yang X, Luo Y, Lu Y, Lin B, Liu T Tags: Biotechnol J Source Type: research