Down-Regulation of Circular RNA_000926 Attenuates Renal Cell Carcinoma Progression through microRNA-411-Dependent CDH2 Inhibition

This study intends to uncover the implication of a novel circRNA circ_000926 in RCC, and how it affects tumorigenesis. Microarray-based circRNA/gene expression profiling of RCC was employed to identify differentially expressed circRNAs/genes in RCC and normal tissues. miRNAs targeting the screened circRNAs/genes were predicted online, followed by analyzing circ_000926 expression in RCC.

Source: American Journal of Pathology - August 29, 2019 Category: Pathology Authors: Dong Zhang, Xiao-Jie Yang, Qi-Dong Luo, De-Lai Fu, Zhao-Lun Li, Peng Zhang, Tie Chong Tags: Regular Article Source Type: research