Combined use of oestradiol and progesterone to support luteal phase in antagonist intracytoplasmic sperm injection cycles of normoresponder women: a case-control study.

In conclusion, our study showed no beneficial effect of addition of E2 to luteal phase support on clinical PR in antagonist IVF cycles. Impact statement What is already known on this subject? Luteal phase deficiency is defined as a disruption in progesterone and oestrogen production after ovulation. It is clear that, luteal phase supplementation to improve the outcomes in in vitro fertilisation (IVF) cycles is mandatory. As an iatrogenic complication of assisted reproductive technique, decreased luteal oestrogen and progesterone levels lead to decreased pregnancy rates (PRs) and implantation rates. What the results of this study add? In this study, we aimed to present the role of luteal phase oestrogen administration in GnRH antagonist cycles. A total of 176 cases received progesterone vaginal gel form for luteal phase support. Study group received 4 mg oral oestradiol hemihydrate in addition to progesterone. Compared to previous studies, our study consisted of larger number of patients and we used oestradiol through oral route. We found out that luteal oestradiol support did not improve the clinical PR. What the implications are of these findings for clinical practice and/or further research? Our study showed no beneficial effect of addition of oestradiol to luteal phase support on clinical PR in antagonist IVF cycles. PMID: 31455122 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research

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Credit: Patrick Burnett/IPSBy Ifeanyi NsoforABUJA, Feb 25 2020 (IPS) Recently, Nigerian feminist author Ukamaka Olisakwe spoke about her post-partum depression after giving birth in the city of Aba, southeast Nigeria. This follows her 2019 Longreads essay, in which she narrated painful details of her experience.  In 2007, Olisakwe was 24 years old when she had her first encounter with post-partum depression. She had just given birth to her first child of three – a daughter. Olisakwe’s experience convinced her that, No one really cares about how the women feel, i...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Global Headlines Health TerraViva United Nations Post-partum depression Source Type: news
Uterine fibroids affect up to 80% of reproductive-aged women. Although many women are asymptomatic, fibroids can cause pelvic pain, abnormal uterine bleeding, anemia, urinary frequency, infertility, and adverse pregnancy outcomes that can impair quality of life. Fifty percent of women with symptomatic fibroids report a detrimental impact on their mental and physical health (1). Fibroids appear to have a greater impact on quality of life than other chronic conditions, including asthma, irritable bowel syndrome, and gastroesophageal reflux disease (2).
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
Publication date: Available online 20 February 2020Source: Case Reports in Women's HealthAuthor(s): Antonella Iannaccone, Marvin Darkwah Oppong, Philipp Dammann, Rainer Kimmig, Angela KöningerAbstractA fetal subdural hematoma (SDH) was diagnosed in a patient with sickle cell disease (SCD) during a routine ultrasound exam in the 30th week of pregnancy. A scan performed a few days earlier had revealed no abnormalities. After interdisciplinary consultation with neurosurgeons and neonatologists, a cesarean section was performed since acute subdural bleeding was hypothesized and the mother's condition was critical. After s...
Source: Case Reports in Womens Health - Category: OBGYN Source Type: research
We present a rare case of metastatic choriocarcinoma.Case presentationA 47-year-old woman presented with shortness of breath, anemia and an elevated serum BhCG level. Her most recent known pregnancy was 12 years previously. Following investigation, she was found to have FIGO stage IV choriocarcinoma with brain metastasis, despite having not experienced any abnormal vaginal bleeding. She was treated with chemotherapy; her treatment was complicated by neutropenic sepsis and a visceral perforation. The patient went into remission and received long-term follow-up.DiscussionIt is unclear in this case whether the disease oc...
Source: Case Reports in Womens Health - Category: OBGYN Source Type: research
Caffeine can easily cross the placenta, and maternal caffeine intake, thus, has an effect on fetal growth. However, it is still unclear whether coffee consumption is an independent risk factor for bleeding in ...
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Research article Source Type: research
TUESDAY, Feb. 18, 2020 -- Progesterone may be beneficial for women with early pregnancy bleeding and a history of miscarriage, according to two studies published online Jan. 30 in the American Journal of Obstetrics&Gynecology and BJOG: An...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
We report the successful anesthetic management of a 31-year-old parturient, on long-term anticoagulant therapy, who presented with acute cardiac tamponade due to perforation of the left atrium from a dislodged atrial septum defect occluder. The cesarean delivery was followed by temporary repair of the perforation without extracorporeal circulation (EC) due to concerns about excessive postpartum bleeding. The definitive repair of the atrial defect and the perforation were successfully accomplished under (EC) 5 days after delivery.
Source: A&A Case Reports - Category: Anesthesiology Tags: Case Reports Source Type: research
Publication date: Available online 13 February 2020Source: Gynecologic Oncology ReportsAuthor(s): Amy L. Alexander, Anna E. Strohl, Kruti P. Maniar, John R. LurainAbstractPlacental site trophoblastic tumor (PSTT) is a rare variant of gestational trophoblastic neoplasia (GTN) that is characterized by slow growth resulting in mostly uterine-confined disease, low human chorionic gonadotropin (hCG) levels, and resistance to chemotherapy.Our objective was to update our center’s experience with PSTT with respect to presentation, prognostic factors, treatment, and outcomes from 2003 to 2019.Thirteen women with PSTT were ide...
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
This study is of great importance in order to decrease the possibility of endangering the lives of fetuses and infants. A combined effort among researchers, scientists, lactating women, and pregnant women may help in changing wrong uses and thoughts about medicinal plants and help to improve the overall health of both mother and fetus.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionsPresence of VBL does not appear to carry additional risk to mother or fetus during pregnancy
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
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