Cancers, Vol. 11, Pages 1263: Health-Related Quality of Life during Chemoradiation in Locally Advanced Rectal Cancer: Impacts and Ethnic Disparities

Conclusion: Chemoradiation for locally advanced rectal cancer affects multiple HRQoL domains. Our findings highlight the importance of psychological aspects of treatment. Significant differences were identified between the Asian and Caucasian populations, with Asians consistently performing worse. Poor correlations between patient and clinician reporting strongly support the inclusion of patient-reported outcomes in clinical studies. HRQoL domains of vomiting and constipation are potential biomarkers of treatment response.

Source: Cancers - August 27, 2019 Category: Cancer & Oncology Authors: Stephanie Hui-Su Lim Emilia Ip Weng Ng Wei Chua Ray Asghari Aflah Roohullah Joseph Descallar Christopher Henderson Kevin Spring Paul de Souza Madeleine T. King Tags: Article Source Type: research