Lower Limb Pulse Rise Time as a Marker of Peripheral Arterial Disease
Objective: The aim of the study was to show if pulse rise times (PRTs) extracted from photoplethysmographic (PPG) pulse waves (PWs) have an association with peripheral arterial disease (PAD) or its endovascular treatment, percutanoeus transluminal angioplasty (PTA) of the superficial femoral artery. Methods: Lower and upper limb PPG PWs were recorded and analyzed from 24 patients who suffered from PAD. The measurements were conducted before and after the treatment, and one month later by using transmission-mode PPG-probes placed in the index finger and second toe. Ankle-to-brachial pressure index and toe pressures were used as references in clinical patient measurements. PRTs, i.e., the time from the foot point to the peak point of the PW, were extracted from the PWs and compared bilaterally. The results from the PAD patients were also compared with 31 same-aged and 34 younger control subjects. Results: Statistically significant differences were found between the pretreatment PRTs of the treated limb of the PAD patients and the same-aged control subjects ($p
We examined trends of SDD, and using 2:1 propensity matching, we assessed 30-day rates of readmission, mortality and total costs at 30 days.ResultsOf 21,261 PCIs from 67 sites, 728 were SDD (3.9% of overall cohort). The rate of SDD increased from 1.6% in 2008 to 9.7% in 2016 (P
We examined temporal trends in VT ablations as compared to other interventional cardiovascular procedures namely, percutaneous coronary intervention (PCI) and atrial fibrillation (AF) ablation in Australia.Methods and ResultsA retrospective review of procedural numbers for VT ablations, AF ablations, and PCI was performed from 2008/09 ‐2016/17 the Australian Institute of Health, Welfare and Aging (AIHW), and Medicare Australia (MA) databases. Linear regression models were fitted to compare the trends in population‐adjusted procedural numbers over the 10‐year period. Data from the AIHW and MA sources respectively show...
In this study we investigated the role of endogenous TSPO in neointima formation after angioplasty in vitro and in vivo. We established a vascular injury model in vitro by using platelet-derived growth factor-BB (PDGF-BB) to stimulate rat thoracic aortic smooth muscle cells (A10 cells). We found that treatment with PDGF-BB (1-20 ng/mL) dose-dependently increased TSPO expression in A10 cells, which was blocked in the presence of PKC inhibitor or MAPK inhibitor. Overexpression of TSPO significantly promoted the proliferation and migration in A10 cells, whereas downregulation of TSPO expression by siRNA or treatment wi...
Randomized clinical trials demonstrated the benefits of percutaneous coronary interventions (PCI) in diverse clinical settings. Patients with cancer were not routinely included in these studies.
Condition: This Study Will Evaluate the Real-world Long-term Clinical Outcome in Chinese Patients Treated With Agent DCB Intervention: Device: AgentTM MONORAILTM Paclitaxel-Coated PTCA Balloon Catheter Sponsor: Boston Scientific Corporation Not yet recruiting
In conclusion, PCI is an effective method of revascularization in patients with ET; but it may be associated with a higher rate of complications including stent thrombus and restenosis. PMID: 31502506 [PubMed - as supplied by publisher]
In conclusion, routine GPI use in morphine-treated STEMI patients undergoing PPCI appears to protect against stent thrombosis. Large-scale studies are needed to establish the overall risk-benefit of GPI therapy in morphine-treated PPCI patients and to assess alternative strategies for preventing acute stent thrombosis in these patients. PMID: 31502505 [PubMed - as supplied by publisher]
ConclusionIn patients with ACS undergoing PCI, CHA2DS2-VASc score can be used as a novel, simple and a sensitive diagnostic tool for the prediction of CIN.
ConclusionsWhen a two-stent strategy is considered in a patient with CBD, the DK-Crush technique reduces DOCE compared to other bifurcation techniques based on all available RCTs.
ConclusionsDespite clear guidelines to avoid surgery early after PCI, NCS was performed in 1 of every 29 patients with recent PCI, corresponding to as many as ~30,000 patients each year nationwide. Surgical mortality and perioperative MI were high in this setting. Strategies to minimize perioperative thrombotic and bleeding risks during readmission for NCS after PCI are necessary.Graphical abstract