Dose-response curves for co-exposure inhalation challenges with ozone and pollen allergen

Exposures to pollen and air pollutants commonly occur simultaneously and have been linked to eliciting or exacerbating the allergic response in susceptible individuals [1, 2]. The risk of co-exposure was recently confirmed in a study from Copenhagen, Denmark [3] indicating that pollen and ozone concentration peaks coincide both diurnally and seasonally. Ozone exposures are able to prime the airways and exacerbate respiratory symptoms [4]. However, this effect is debated, especially regarding lower and more commonly naturally occurring exposures [5, 6].

Source: European Respiratory Journal - August 21, 2019 Category: Respiratory Medicine Authors: Orby, P. V., Bonlokke, J. H., Bibby, B. M., Ravn, P., Hertel, O., Sigsgaard, T., Schlünssen, V. Tags: Original Articles: Research letters Source Type: research