Do shared semantic features facilitate Lexical-semantic processing in early course psychosis?

Do shared semantic features facilitate Lexical-semantic processing in early course psychosis? Clin Linguist Phon. 2019 Aug 20;:1-9 Authors: Sekulić Sović M, Erdeljac V, Kužina I Abstract The lexical-semantic relatedness effect supposes different activation in the semantic memory of related versus unrelated word-pairs. Semantically related pairs are considered to result in a larger spread of activation as the activation of concept nodes is dependent on shared lexical-semantic features of concepts. The increased activation of concepts in the semantic memory in individuals with schizophrenia is found to be, faster spreading and lacking in inhibition in relation to healthy control subjects. The aim of this study was to examine whether the lexical-semantic relatedness effect influences processing in individuals with early course psychosis by utilizing an explicit semantic matching task with 0ms SOA (Stimulus Onset Asynchrony) to analyse the strategy-free automatic spreading activation process. Overall, the patient group had lower accuracy and longer reaction times compared with healthy subjects, as well as better accuracy for related word-pairs and longer reaction times are for unrelated word-pairs. In clinical practice, the determination of language classifiers for early course psychosis could potentially enable the creation of reliable diagnostic markers and instruments for identifying the population with an elevated risk ofdeveloping disorders with...
Source: Clinical Linguistics and Phonetics - Category: Speech-Language Pathology Authors: Tags: Clin Linguist Phon Source Type: research

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In conclusion, this study found that patients with FES had abnormal functional connectivity in the amygdala subregions, and the altered rsFC was associated with positive symptoms. The present findings demonstrate the disruptive rsFC patterns of amygdala subregional-sensorimotor networks in FES and may provide new insights into the neuronal pathophysiology of FES.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Severe infection is linked to an increased risk of substance-induced psychosis. However, hepatitis is the most strongly linked and the only infection tied to schizophrenia conversion.Medscape Medical News
Source: Medscape Infectious Diseases Headlines - Category: Infectious Diseases Tags: Psychiatry News Source Type: news
Conclusion This study shows meaningful clinical effectiveness and good tolerability of mECT in patients with resistant schizophrenia over extended periods.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
Objective The aim of this study was to report the efficacy and safety of electroconvulsive therapy (ECT) in manic, depressed, psychotic, and catatonic adolescent patients. Methods Medical records of 78 adolescents who had received ECT in Department of Psychiatry, Gaziantep University Medical Faculty, during 2011 to 2017 were reviewed. Sixty-two subjects in this sample were identified to have complete records and met the study inclusion criteria. Results The mean ± SD age of subjects was 17.11 ± 1.04 years and female sex was 53.2% (n = 33). Primary the Diagnostic and Statistical Manual of Mental Disord...
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
No abstract available
Source: The Journal of ECT - Category: Psychiatry Tags: Letter to the Editor Source Type: research
AbstractNicotinic acetylcholine receptors (nAChRs) are major signalling molecules in the central and peripheral nervous system. Over the last decade, they have been linked to a number of major human psychiatric and neurological conditions, like smoking, schizophrenia, Alzheimer's disease, and many others. Human Genome ‐Wide Association Studies (GWAS) have robustly identified genetic alterations at a locus of chromosome 15q to several of these diseases. In this review, we discuss a major coding polymorphism in the alpha5 subunit, referred to as α5SNP, and its functional dissectionin vitro andin vivo. Its presence at...
Source: Journal of Neurochemistry - Category: Neuroscience Authors: Tags: REVIEW Source Type: research
Several studies have found that patients with schizophrenia experience cognitive benefits from exercise. Astudy inPsychiatric Research suggests schizophrenia patients who participate in a 12-week aerobic exercise program may continue to experience cognitive benefits months after the program ends.“These findings encourage the incorporation of [aerobic exercise] in psychosocial treatment regimens [for schizophrenia],” wrote Takeshi Shimada, Ph.D., of the Medical Corporation Seitaikai Mental Support Soyokaze Hospital in Japan and colleagues.Shimada and colleagues conducted a randomized trial in which patients were...
Source: Psychiatr News - Category: Psychiatry Tags: Brief Assessment of Cognition in Schizophrenia exercise group exercise psychiatric research schizoaffective disorders Takeshi Shimada Source Type: research
Condition:   Schizophrenia Intervention:   Other: Evoked Related Potentials Sponsor:   Centre Hospitalier Universitaire de Nice Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Schizophrenia Intervention:   Behavioral: Cognitive Remediation Therapy Sponsors:   Hospital Clinic of Barcelona;   National Alliance for Research on Schizophrenia and Depression;   Instituto de Salud Carlos III Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Schizophrenia; Psychosis Intervention:   Drug: Levetiracetam 500 mg Sponsor:   Vanderbilt University Medical Center Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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