Serum B cell maturation antigen (BCMA) levels differentiate primary antibody deficiencies

ConclusionsBCMA is profoundly reduced in severe PAD, including CVID, XLA and subjects with IgG < 600 mg/dL. sBCMA measurement has potential to augment clinical evaluation of PAD. Prospective studies are needed to evaluate sBCMA for new PAD diagnosis and determining necessity of IRT.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research