A Lesson in Screening For Hereditary Kidney Cancer Syndromes A Lesson in Screening For Hereditary Kidney Cancer Syndromes
This case of a renal cell carcinoma in a 30-year-old highlights the need for screening for hereditary kidney cancer syndromes in patients diagnosed with RCC at a young age.Urologic Nursing
DiscussionUp to now, only 105 cases of occurring renal SFT have been reported. SFTs are usually asymptomatic when they have a small size, that’s why the diagnosis is often delayed. Blood tests do not have any diagnostic value. Imaging features are not specific for the diagnosis of SFT which are diagnosed as renal cell carcinoma and treated as such. Typical immunohistochemical characteristic is a high positivity for CD34. As SFT has a malignant potential, careful follow-up is mandatory,searching for local recurrence or metastasis which was reported in few cases.ConlusionSFTs are indolent tumors and are usually diagnos...
We report the development of hidradenitis suppurativa (HS) in a patient after initiation of treatment with sorafenib. To our knowledge, sorafenib-induced HS in the axillary and inguinal skin folds has not been previously reported. A 33-year-old male on sorafenib for papillary thyroid cancer presented for evaluation of “boils” that began when he initiated chemotherapy 5 years prior and had continued to progress.
Condition: Carcinoma, Renal Cell Interventions: Other: Laboratory analysis of samples; Other: Application of machine learning Sponsor: CCTU- Cancer Theme Not yet recruiting
Tumor targeting small molecular inhibitors are the most popular treatments for many malignant diseases, including cancer. However, the lower clinical response and drug resistance still limit their clinical eff...
Semin intervent Radiol 2019; 36: 183-193 DOI: 10.1055/s-0039-1694714With the increased incidence of stage T1a renal cell carcinoma (RCC) has come the recognition that these lesions tend to be low grade and slow growing, with low probability of metastasis not necessarily requiring surgery. As alternatives to surgery, both active surveillance and ablation have been advocated for the management of selected patients with stage T1a renal cancers due to slow rate of tumor growth and low metastatic potential based on recent epidemiological studies. Thermal ablation also has consistently reported favorable complication and renal p...
This article discusses the epidemiology of renal cell cancers; discusses the current management guidelines from multiple specialty societies; discusses some of the surgical and interventional techniques used in the treatment of such lesions; and provides a review of the literature regarding treatments of early-stage renal cell cancers. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Abstract | Full text
CONCLUSION: We hypothesise that this approach has the potential to reveal novel information about the heterogeneity and evolutionary trajectory of spatiotemporal tumour samples, potentially revealing early events in tumorigenesis and the origins of metastases and recurrences. PMID: 31424551 [PubMed - as supplied by publisher]
This meta-analysis was performed to evaluate the relationship between hypoxia-inducible factor-1 α (HIF1α) 1790G/A gene polymorphism and the susceptibility to renal cell carcinoma (RCC) and prostate cancer (PCa).
ConclusionThe current results demonstrated that PVT1 and EGOT could serve as potential biomarkers of ccRCC with good performance characteristics.