The expression and functionality of stromal caveolin 1 in human adenomyosis
This study assessed the functional role of stromal CAV1 and RANTES in a small number of human adenomyosis samples by immunohistochemistry and in primary human ESCs by functional studies. In future investigations, a larger sample size should be adopted and the functional role of stromal CAV1 should be further characterized in animal models.
WIDER IMPLICATIONS OF THE FINDINGS
Loss of stromal CAV1 expression may play a critical role in the pathogenesis of adenomyosis and is correlated with adenomyosis-related dysmenorrhea.
STUDY FUNDING
National Basic Research Program of China and Ph.D. Programs Foundation of Ministry of Education of China.
COMPETING INTEREST
None.
Source: Human Reproduction - Category: Reproduction Medicine Authors: Zhao, L., Zhou, S., Zou, L., Zhao, X. Tags: Reproductive biology Source Type: research
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