Patterns of utilization and comparative efficacy of altered fractionation and concurrent chemoradiation for treatment for T2N0M0 glottic carcinoma

ConclusionsHypofractionation gave superior survival than standard fractionation for glottic T2N0M0 tumors. Its use varies among treatment centers but is increasing with time. Chemoradiation gave a lower therapeutic ratio: more than 30% greater acute toxicity without improvement of survival; yet, its use is growing over time. More explicit guidelines are needed.
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research