Dosimetric comparison of supine versus prone radiotherapy techniques in patients with breast cancer
ConclusionThe prone position for the radiotherapy treatment of left breast cancer was dosimetrically better than the supine position in terms of mean dose to the heart and left lung. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 18, 2020 Category: Cancer & Oncology Source Type: research

SBRT re-irradiation after prior SBRT in pancreatic cancer —outcomes and a focus on stomach and bowel toxicity
ConclusionSBRT after prior SBRT for pancreatic cancer is a reasonably safe and efficacious treatment that leads to durable local control and reasonable survival. Retreatment of the duodenum and stomach with a D0.03cc and D1cc of at least 40  Gy may be safe, although more data is needed. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 15, 2020 Category: Cancer & Oncology Source Type: research

Stereotactic body radiation therapy for early-stage non-small cell lung cancer in the USA: patterns of adoption and potential healthcare disparities
ConclusionSBRT use is increasing across all treatment facilities but there are notable health disparities based on socioeconomic factors including race that may be contributing to worse survival outcomes. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 2, 2020 Category: Cancer & Oncology Source Type: research

Feasibility of simulation contrast-enhanced computed tomography (CECTSim) of the head and neck region to detect early nodal recurrence in postoperative oral squamous cell carcinoma in a resource-constrained setup
ConclusionCECTSim may be helpful in the detection of EPNR in OSCC and may preclude the need for additional imaging before the start of PORT. CECTSim may also facilitate the appropriate determination of the radiation volume and appropriate dose to the corresponding target volume. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 1, 2020 Category: Cancer & Oncology Source Type: research

Indirect evaluation of pretreatment imaging protocols and their clinical impact on patient dose delivery in radiotherapy
ConclusionThis study plays a vital role in establishing optimum pretreatment imaging protocols in busy clinics. Three days a week imaging protocol is the best suit protocol found with minimal deviation and ample implementation feasibility. This study proposed an opinion pertaining to the revision of setup margin formula in order to accommodate variation due to imaging techniques and frequency of imaging attempted during radiotherapy. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - November 26, 2020 Category: Cancer & Oncology Source Type: research

Feasibility of simulation contrast-enhanced computed tomography (CECT Sim ) of the head and neck region to detect early nodal recurrence in postoperative oral squamous cell carcinoma in a resource-constrained setup
ConclusionCECTSim may be helpful in the detection of EPNR in OSCC and may preclude the need for additional imaging before the start of PORT. CECTSim may also facilitate the appropriate determination of the radiation volume and appropriate dose to the corresponding target volume. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - November 18, 2020 Category: Cancer & Oncology Source Type: research

Impact of lung tumor motion on dose delivered to organ at risk in lung stereotactic body radiation therapy
ConclusionThe dose received by the OARs depends on the amplitude of tumor motion and is relative to the OAR ’s location and motion, due to patient respiration and heart contribution. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - November 10, 2020 Category: Cancer & Oncology Source Type: research

Dosimetric evaluation of a rotating gamma-ray system for stereotactic body radiation therapy
ConclusionThe new CybeRay machine showed promising dosimetric capabilities for stereotactic radiosurgery and radiotherapy of extra- and intra-cranial lesions. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - October 21, 2020 Category: Cancer & Oncology Source Type: research

Efficacy of palliative SBRT in local control of sarcoma
ConclusionOur institutional experience provides encouraging evidence of the feasibility of SBRT in the palliation of sarcoma. Poor overall survival is a substantial competing risk in these patients. Further studies will be required to identify the ideal dose and fractionation across histological subtypes. Prospective clinical trials may be warranted. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - October 20, 2020 Category: Cancer & Oncology Source Type: research

Early detection of SARS-CoV-2 from staging PET-CT
ConclusionIn the COVID-19 era, oncologists obtaining routine staging imaging should have high diagnostic suspicion for subclinical SARS-CoV-2 infection. To avoid precipitating severe pneumonia and hospitalization, multidisciplinary discussion with risk-benefit analysis is recommended before initiating immunosuppressive therapies such as chemoradiation. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - September 28, 2020 Category: Cancer & Oncology Source Type: research

Dosimetric comparison of three-dimensional conformal radiotherapy and static and dynamic intensity-modulated radiotherapy for the treatment of early-stage glottic cancer
ConclusionThe D-IMRT and S-IMRT techniques allowed more homogeneous dose distributions in PTV. Considering the dose to OAR, S-IMRT was more appropriate rather than 3DCRT and D-IMRT. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - September 18, 2020 Category: Cancer & Oncology Source Type: research

A comparison of quality of life and acute toxicity in patients applied with Tomo-helical IMRT and conformal radiotherapy for breast cancer
ConclusionThe findings of RT toxicity and quality of life appear to be superior in patients applied with Tomo-helical IMRT compared with patients treated with 3D-CRT. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - August 30, 2020 Category: Cancer & Oncology Source Type: research

An observational study of post-operative volumetric modulated arc radiotherapy (VMAT) of breast cancer by immobilizing patients on All-in-One (AIO ™) solution breast and lung board without using thermoplastic mask: risk of collision of gantry with couch exists if acquisition of Cone Beam Computed Tomography (CBCT) is attempted for set-up verification
ConclusionPerforming CBCT for generating 3D images for computed tomography (CT) reconstruction may not be practical for patient set-up verification of post-operative radiotherapy of unilateral breast cancer patients positioned supine on breast and lung board. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - August 28, 2020 Category: Cancer & Oncology Source Type: research

Whole breast irradiation with high tangents in the prone position
ConclusionsThis series demonstrates the feasibility of high tangents in the prone position, offering good coverage of level I LN, particularly with<  1 cm distance from the humeral head. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - August 24, 2020 Category: Cancer & Oncology Source Type: research

Peer review program to enhance treatment planning quality assurance for community radiation oncologists
ConclusionA two-step QA program was considered highly valuable by all participants allowing easily implanted mechanisms for standardization, higher case volume, and shared educational resources for small academic satellite CROs who are faced with the challenge of caring for a diverse community cancer population. Feasibility suggests the model could serve as a model for other CRO. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - July 29, 2020 Category: Cancer & Oncology Source Type: research