The proceedings of the radiation oncology summit: acro 2019
(Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - June 13, 2019 Category: Cancer & Oncology Source Type: research

Neoadjuvant chemotherapy and high-dose radiation using intensity-modulated radiotherapy followed by rectal sparing TEM for distal rectal cancer
ConclusionsHigh-dose IMRT and chemotherapy followed by FTLE to treat distal rectal cancers are well tolerated and effective. FTLE may improve outcomes and minimize complications in appropriately selected patients. Randomized clinical trials are needed to compare it with standard surgery. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - May 30, 2019 Category: Cancer & Oncology Source Type: research

A risk model for lung complication combining radiation therapy and chronic obstructive pulmonary disease
AbstractPurposeTo develop a multi-variate risk model of lung complication for the treatment of locally advanced lung cancer combining radiation dosimetry and patient-specific risk factors including chronic obstructive pulmonary disease (COPD).Materials/methodsA retrospective study of 89 advanced lung cancer patients including clinical variables and radiation dose-volume metrics was correlated to overall survival (OS), local progression-free survival (LPFS), and lung complications. Lung toxicities were defined as grade 2 or higher lung complication including persistent cough requiring narcotic or antitussive agents, and dys...
Source: Journal of Radiation Oncology - May 28, 2019 Category: Cancer & Oncology Source Type: research

Effect of intermittent low-dose irradiation on the radiotherapy efficiency for MDA-MB-231 human breast adenocarcinoma cell line
AbstractIntroductionDespite the fact that high-dose radiotherapy is a main therapeutic modality in cancer treatment, recent evidence suggests that it might confer radioresistance. Hyper-radiosensitivity (HRS) is one of the important biological effects of low-dose ionizing radiation (LDIR) in mammalian cell lines. LDIR is considered as a promising assistant method of clinical cancer therapy. The purpose of this study was to evaluate the efficiency of intermittent LDIR followed by a high-dose radiation therapeutic approach compared with the conventional high-dose radiotherapy in the breast cancer MDA-MB-231 cell line.Materia...
Source: Journal of Radiation Oncology - May 25, 2019 Category: Cancer & Oncology Source Type: research

Fast in situ image reconstruction for proton radiography
ConclusionWe have demonstrated, through computer simulations of proton irradiation of a pediatric head phantom using the newly built pRad detector and image reconstruction software, that high-quality proton radiographs can be generated for patient alignment and verification of water equivalent thickness of the patient before each treatment. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - May 25, 2019 Category: Cancer & Oncology Source Type: research

Whiteboard patient tracking system improves radiation oncology treatment planning workflow
In this study, we compare the time required for completion of several components of this process, before and after whiteboard implementation, hypothesizing that whiteboard usage would decrease the time required to complete the designated task, thereby improving workflow.MethodsWe retrospectively reviewed dosimetric workflow data from 578 patients treated between January 2015 and January 2017 (320 pre- and 258 post-whiteboard). The whiteboard system cataloged various patient clinical factors as well as workflow metrics. Departmental workflow was then examined and time from simulation date to contour approval, plan approval,...
Source: Journal of Radiation Oncology - May 6, 2019 Category: Cancer & Oncology Source Type: research

Changes in prostate-specific antigen midway through salvage radiotherapy may be associated with long-term outcomes
ConclusionsPSA changes by the midpoint of SRT predict long-term prostate cancer control with increases in PSA associated with decreased freedom from disease progression. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - May 2, 2019 Category: Cancer & Oncology Source Type: research

Lymphopenia as a predictor of survival in chemoradiation-treated stage III non-small-cell lung cancer (NSCLC): a multi-center retrospective analysis
AbstractBackgroundConcurrent chemoradiation (CRT) with a platinum-containing regimen is considered standard of care for eligible unresectable stage III non-small-cell lung cancer (NSCLC) patients. Attempts to improve locoregional control, and thereby enhance overall survival (OS), by increasing the dose of radiation failed to do so in a contemporary phase III trial. Better understanding of the effects of radiation on the immune system, particularly absolute lymphocyte counts (ALC), may explain the poorer survival seen with high-dose (HD) radiation compared to low dose (LD). We hypothesized that treatment-induced lymphopeni...
Source: Journal of Radiation Oncology - April 29, 2019 Category: Cancer & Oncology Source Type: research

Adjuvant chemoradiation in resected gallbladder cancer: a prognostic index model for predicting overall survival
AbstractPurposePatients with gallbladder cancer (GBC) have a dismal prognosis. We investigated outcomes and risk factors for overall survival (OS) in patients treated with radical surgery and adjuvant chemoradiotherapy (CRT).Materials/methodsA total of 212 patients with LAGC ( ⩾pT3 59% and/or pN+ 52%) were studied. The primary endpoint of the analysis was OS. We constructed a risk scoring system in which points were assigned to each risk factor by dividing each β coefficient in the final model by the lowest β coefficient and rounding to the nearest integer. A risk sco re was assigned to each subject by adding u...
Source: Journal of Radiation Oncology - March 26, 2019 Category: Cancer & Oncology Source Type: research

Correction to: Stereotactic body radiation therapy for non-small cell lung cancer patients with prior history of thoracic surgery and/or radiation therapy: the influence of smoking, size, and central location on risk of complications
The article Stereotactic body radiation therapy for non-small cell lung cancer patients with prior history of thoracic surgery and/or radiation therapy: the influence of smoking, size, and central location on risk of complications. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 23, 2019 Category: Cancer & Oncology Source Type: research

Comparison of deep inspiration breath hold and free breathing technique in left breast cancer irradiation: a dosimetric evaluation in 40 patients
ConclusionOur study confirms the DIBH technique advantage in reducing cardiac and pulmonary doses for tangentially treated left-sided breast cancer patients. Further research is warranted to evaluate potential long-term clinical implications of these relevant dosimetry results. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 19, 2019 Category: Cancer & Oncology Source Type: research

Reconstructed and real proton radiographs for image-guidance in proton beam therapy
AbstractOne of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target volume along the direction of the beam to ensure safety and tumor target coverage.Proton radiography holds promise as both an image-guidance method for proton beam therapy and as a means of estimating particle beam range in the clinic. In this brief report, we present some of the first real and reconstructed proton radio...
Source: Journal of Radiation Oncology - March 19, 2019 Category: Cancer & Oncology Source Type: research

Use of the neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) for prognostication of patients with early-stage non-small cell lung cancer (NSCLC) treated with stereotactic body radiation therapy (SBRT): a systematic review
ConclusionNLR and PLR appear to be relevant prognostic factors for OS following lung SBRT in stage I NSCLC. They may serve as accessible and inexpensive tests to aid in clinical decision-making but prospective validation is necessary. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 19, 2019 Category: Cancer & Oncology Source Type: research

Prostate radiotherapy effects on testosterone levels: an empirical investigation
AbstractObjectiveThere is a paucity of clinical data to support the hypothesis that external beam radiation therapy causes iatrogenic hypogonadism in prostate cancer patients.MethodsAll prostate cancer patients treated at a single institution with radiation therapy between 2002 and 2010 were retrospectively evaluated. Patients treated with brachytherapy alone received 0  Gy of external beam radiation therapy and served as the control group. Patients treated with combination external beam radiation therapy + brachytherapy, or external beam radiation therapy alone were categorized into groups who received 45–54&nb...
Source: Journal of Radiation Oncology - March 18, 2019 Category: Cancer & Oncology Source Type: research

Targeted therapy combined with thoracic radiotherapy for non-small cell lung cancer
ConclusionsIn this review, we summarize the recent literature about the use of molecularly targeted agents with concurrent RT in NSCLC patients. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 14, 2019 Category: Cancer & Oncology Source Type: research

Rectal wall delineation in patients with a rectal displacement device in place during prostate cancer radiotherapy
(Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 7, 2019 Category: Cancer & Oncology Source Type: research

Reduced acute and late toxicities with intensity-modulated radiation therapy compared to three-dimensional conformal radiation therapy in post-operative gastric cancer
ConclusionsUse of IMRT in post-operative gastric cancer is associated with reduced acute and late toxicities. Consideration should be given for prospective evaluation in the future. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - February 14, 2019 Category: Cancer & Oncology Source Type: research

Radiotherapy for parotid malignancies: patterns of care and impact on overall survival
ConclusionsOur data suggests that PORT was associated with improved survival. Additionally, some subgroups may receive additional benefit and patients with small (T1), low-grade disease may be able to forgo PORT. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - February 2, 2019 Category: Cancer & Oncology Source Type: research

Volume effects in radiosurgical spinal cord dose tolerance: how small is too small?
ConclusionsDmax has greater variability compared to D0.03  cc, D0.1 cc, and D1 cc, potentially creating risks when used for guidance for spinal cord. D0.03 cc may be an attractive alternative with higher reliability while its limits could be obtained by scaling the reported Dmax limit by a factor of 0.93. This may help guide treatment planning and aid in discovering true dose constraints for spine SBRT. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - January 31, 2019 Category: Cancer & Oncology Source Type: research

Ductal carcinoma in situ (DCIS) breast cancer treated with 3-week accelerated hypofractionated whole-breast radiation therapy and concomitant boost
ConclusionThe HF schedule with CB in DCIS patients is well tolerated and associated with excellent clinical outcomes. This schedule affords the benefit of delivering higher dose to the lumpectomy site without protracting overall treatment time. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - January 26, 2019 Category: Cancer & Oncology Source Type: research

Results of a pilot/phase II study of gamma knife radiosurgery for brain metastases and implications for future prospective clinical trials
ConclusionIn this pilot/phase II study, we learned: (1) radiosurgery using radiation doses based on our algorithm provides good local control with low toxicity. (2) Despite the relative commonality of brain metastases, patients with brain metastases are difficult to enroll on clinical trials. (3) A prospective study that encompasses all potentially important clinical variables that go into radiosurgery dose selection will require large amounts of patients. Our findings have important implications for future clinical trials of radiosurgery for brain metastases. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - January 14, 2019 Category: Cancer & Oncology Source Type: research

Five-year results of post-prostatectomy patients administered a hydrogel rectal spacer implant in conjunction with dose escalated external beam radiation therapy
ConclusionHydrogel rectal spacer implants in patients who previously had a prostatectomy is well tolerated long term with reduced incidence of GI and GU toxicities, and bRFS rates consistent with previous reports in the literature. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 18, 2018 Category: Cancer & Oncology Source Type: research

Ventricular violation increases the risk of leptomeningeal disease in cavity-directed radiosurgery treated patients
ConclusionsLMD incidence is relatively high in patients receiving postoperative cavity-directed SRS. Ventricular violation during surgery causes a significantly higher risk of LMD, and consideration of WBRT, greater SRS target volumes, or preoperative treatment in these patients may be warranted. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 18, 2018 Category: Cancer & Oncology Source Type: research

Clinical evidence for dose tolerance of the central nervous system in hypofractionated radiotherapy
ConclusionsEffective differences between single fraction SRS and conventional radiotherapy need to be better understood. The existing biological model might not be valid to predict the radiosurgical outcomes based on conventionally fractionated radiotherapy. However, application of the statistical dose response models of clinical SRS and SBRT outcomes data to selected current dose tolerance guidelines into simple tables can be a clinically useful resource. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 3, 2018 Category: Cancer & Oncology Source Type: research

Inter-fraction movements of the prostate and pelvic lymph nodes during IGRT
ConclusionLymph nodes and prostate were most mobile in the A-P direction, followed by the C-C and R-L directions. This movement should be taken into account when deciding the margins for the planning target volumes (PTV). (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - November 28, 2018 Category: Cancer & Oncology Source Type: research

Experience with hypofractionated stereotactic radiosurgery in a series of patients with skull base tumors
ConclusionsIn our series of patients, the high incidence of non-progression of tumors indicated that HSRS could be a therapeutic option in some cases of skull base lesions, mainly residuals or tumoral recurrences of pituitary adenomas, schwannomas, and meningiomas. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - November 22, 2018 Category: Cancer & Oncology Source Type: research

Relationship among different skin dose definitions in high-dose-rate (HDR) balloon breast brachytherapy
ConclusionThe presented relationships can be developed in each individual institution and convert one dosimetric index to another for different skin definitions. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - November 17, 2018 Category: Cancer & Oncology Source Type: research

Acute toxicities after volumetric modulated arc therapy for craniospinal irradiation in adults
ConclusionsVMAT radiation delivery is feasible and well tolerated in adult patients receiving CSI. The addition of adjuvant chemotherapy carries an increased risk for hematologic toxicity. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - November 15, 2018 Category: Cancer & Oncology Source Type: research

Evaluation of effectiveness of palliative radiotherapy for bone metastases: a prospective cohort study
ConclusionCompared to randomized trial populations, palliative radiotherapy in our unselected patients with bone metastases showed similar pain response rates (61%), with a reasonable duration of this effect. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - November 10, 2018 Category: Cancer & Oncology Source Type: research

A fiducial-less tracking method for radiation therapy of liver tumors by diaphragm disparity analysis part 2: validation study by using clinical data
ConclusionWe proposed and investigated the fiducial-less tracking method to follow tumor motion in the real-time under the influence of respiration. The study shows the feasibility of accurately predicting the tumor ’s position with the use of lung-diaphragm border’s information through available kV images without gold fiducial markers. This developed diaphragm disparity-analysis-based approach, verified with clinically accepted errors, has the potential to replace fiducial markers in clinical applications. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - October 18, 2018 Category: Cancer & Oncology Source Type: research

In memoriam: the legendary Dr. Luther Brady —founding ACRO president and founding JRO editor in chief
(Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - September 6, 2018 Category: Cancer & Oncology Source Type: research

The effects of treatment duration on outcomes of radiation treatment with high-dose-rate brachytherapy in the era of concurrent chemoradiation for cervical carcinoma
ConclusionsIn the present era of HDR-ICBT with CCRT, radiation treatment longer than 8  weeks does not appear to make a significant impact on clinical outcomes. This is a retrospective analysis. Further studies are warranted. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

The albumin-bilirubin (ALBI) model in hepatocellular carcinoma (HCC) may better predict hepatic failure in patients with traditionally low-risk cirrhosis following definitive stereotactic body radiotherapy (SBRT)
ConclusionOur study indicates that the ALBI index more precisely predicted liver failure and survival in HCC following SBRT compared to CP scoring. Its application may help select the most ideal candidates for SBRT among the often heterogeneous CP-A population. Further study regarding precautionary measures such as functional treatment planning for ALBI-2 patients treated with liver SBRT may be warranted. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Factors predictive of neoadjuvant versus adjuvant chemoradiotherapy in locally advanced rectal cancer and the impact on overall survival
AbstractObjectivesWe investigated the effect of neoadjuvant versus adjuvant chemoradiotherapy on overall survival as well as the impact of demographic and clinical factors for the selection of each approach utilizing the National Cancer Data Base.MethodsAdult patients with stage II and stage III adenocarcinoma of the rectum diagnosed from 2004 to 2013 were included. Chi-square analysis was used to compare demographic variables and clinical stage between the patients receiving neoadjuvant and adjuvant chemoradiotherapy. Univariate and multivariate logistic regression modeling was used to identify factors predictive of each ...
Source: Journal of Radiation Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

A phase II trial to determine the cosmetic outcomes and toxicity of 27  Gy in five-fraction accelerated partial breast irradiation: the ACCEL trial
ConclusionsThis trial will assess the cosmetic and normal tissue outcomes of external beam APBI delivered in 1  week for early-stage breast cancer.Trial registrationRegistration number: NCT02681107 (clinicaltrials.gov), registered February 2, 2016. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Reducing radiation dermatitis during ongoing radiation therapy: an innovative film-forming wound dressing
AbstractObjectiveThis multicenter study focuses on the use of a film-forming wound dressing in the form of a gel that can be applied directly to the area affected by radiation dermatitis, especially after skin breakdown. The primary objective of the study was to validate the efficacy of an innovative film-forming wound dressing used as monotherapy in the treatment of radiation dermatitis in patients with RTOG score 2.5 ( ± 0.5) confirmed by the investigator.MethodsFifty-four patients undergoing radiation therapy for different cancer types and developing radiation dermatitis were recruited in the study; they w...
Source: Journal of Radiation Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Stereotactic radiosurgery practice patterns for brain metastases in the United States: a national survey
AbstractBackgroundStereotactic radiosurgery (SRS) has emerged as an important modality for the treatment of intracranial metastases. There are currently few established guidelines delineating indications for SRS use and fewer still regarding plan evaluation in the treatment of multiple brain metastases.MethodsAn 18 question electronic survey was distributed to radiation oncologists at National Cancer Institute (NCI) designated cancer centers in the USA (60). Centers without radiation oncologists were excluded. Physicians who indicated that they do not prescribe SRS were excluded from the remaining survey questions. Sign te...
Source: Journal of Radiation Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

A fiducial-less tracking method for radiation therapy of liver tumors by diaphragm disparity analysis part 1: simulation study using machine learning through artificial neural network
ConclusionThis simulation study shows that the diaphragm and tumor position are closely related. The developed diaphragm disparity-analysis approach, featuring tracking capability and verified with clinically acceptable errors, has the potential to replace fiducial markers for clinical application. The tracking method will be further investigated in clinical datasets from patients. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Re-irradiation in gynecological cancers, present experiences and future hopes
ConclusionThe results of salvage re irradiation are reasonable.  More upcoming evidences and ongoing technological innovations will guide us in more effective retreatment and addition to life in this group of patients. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

A comprehensive analysis of clinical trials including both immunotherapy and radiation therapy
AbstractPurposeRadiation therapy (RT) may work synergistically with cancer immunotherapies but clinical trial data is needed to validate this paradigm. We isolated the portfolio of trials that investigate the primary immunomodulatory properties of RT and examined recent trends in clinical trials that combine immunotherapy and RT (ITRT).MethodsWe queriedclinicaltrials.gov for trials initiated since 2002 using both radiation and immunotherapy as mandated interventions. We designated the trials that examine the specific aspects of RT or its abscopal properties as “Primary RT Immunomodulation” trials. Chi-squared a...
Source: Journal of Radiation Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Tolerability of sequential immune therapy and palliative radiotherapy to the cervical and thoracic spine
ConclusionsCombined immune therapy and radiotherapy for palliation of spine metastases suggests increased toxicity when a greater number of vertebral bodies are irradiated, or when combined immune therapy agents are utilized. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

In memoriam: the legendary Dr. Luther Brady —founding ACRO president and founding JRO editor in chief
(Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

A phase II trial to determine the cosmetic outcomes and toxicity of 27  Gy in five-fraction accelerated partial breast irradiation: the ACCEL trial
ConclusionsThis trial will assess the cosmetic and normal tissue outcomes of external beam APBI delivered in 1  week for early-stage breast cancer.Trial registrationRegistration number: NCT02681107 (clinicaltrials.gov), registered February 2, 2016. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - August 2, 2018 Category: Cancer & Oncology Source Type: research

A fiducial-less tracking method for radiation therapy of liver tumors by diaphragm disparity analysis part 1: simulation study using machine learning through artificial neural network
ConclusionThis simulation study shows that the diaphragm and tumor position are closely related. The developed diaphragm disparity-analysis approach, featuring tracking capability and verified with clinically acceptable errors, has the potential to replace fiducial markers for clinical application. The tracking method will be further investigated in clinical datasets from patients. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - July 24, 2018 Category: Cancer & Oncology Source Type: research

Reducing radiation dermatitis during ongoing radiation therapy: an innovative film-forming wound dressing
AbstractObjectiveThis multicenter study focuses on the use of a film-forming wound dressing in the form of a gel that can be applied directly to the area affected by radiation dermatitis, especially after skin breakdown. The primary objective of the study was to validate the efficacy of an innovative film-forming wound dressing used as monotherapy in the treatment of radiation dermatitis in patients with RTOG score 2.5 ( ± 0.5) confirmed by the investigator.MethodsFifty-four patients undergoing radiation therapy for different cancer types and developing radiation dermatitis were recruited in the study; they w...
Source: Journal of Radiation Oncology - July 20, 2018 Category: Cancer & Oncology Source Type: research

The effects of treatment duration on outcomes of radiation treatment with high-dose-rate brachytherapy in the era of concurrent chemoradiation for cervical carcinoma
ConclusionsIn the present era of HDR-ICBT with CCRT, radiation treatment longer than 8  weeks does not appear to make a significant impact on clinical outcomes. This is a retrospective analysis. Further studies are warranted. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - July 17, 2018 Category: Cancer & Oncology Source Type: research

The use of stereotactic radiosurgery for benign spinal tumors: single institution experience
ConclusionThe results of SRS for benign tumors of the spine appear to be promising, and as a result SRS may have a role in treating benign spinal tumors for patients who are not surgical candidates. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - June 1, 2018 Category: Cancer & Oncology Source Type: research

The proceedings of the radiation oncology summit: acro 2018
(Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - June 1, 2018 Category: Cancer & Oncology Source Type: research

Comparison between CT- and MRI-derived head and neck cancer target volumes using an integrated MRI-tri- 60 Co teletherapy device
ConclusionSignificant differences in GTV extent were noted between MRI- and CT-derived ViewRay images. The implications for treatment planning are discussed. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - June 1, 2018 Category: Cancer & Oncology Source Type: research

Effect of BioZorb ® surgical marker placement on post-operative radiation boost target volume
ConclusionThe BioZorb ® arm showed statistically significant reductions in CTV and PTV but not ipsilateral lung or heart irradiation. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - June 1, 2018 Category: Cancer & Oncology Source Type: research