Induction and rejoining of DNA double-strand breaks in the lymphocytes of prostate cancer patients after radium-223 treatment as assessed by the γH2AX foci assay.

CONCLUSION: Our findings indicate that the number of γH2AX foci per cell was not changed in dependence on the Ra-223 therapy cycles. The ability of patient's lymphocytes to repair ex vivo induced DSB remained unaffected throughout the entire therapy course. PMID: 31387125 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31387125?dopt=Abstract

Source: Nuklearmedizin - August 5, 2019 Category: Radiology Authors: Runge R, Oehme L, Grosche-Schlee S, Braune A, Freudenberg R, Kotzerke J Tags: Nuklearmedizin Source Type: research